Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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88 genes differentially expressed following the BRD-K13390322_AT-7519_A375_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
AREG | amphiregulin |
ATF3 | activating transcription factor 3 |
BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
BTG3 | BTG family, member 3 |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CD36 | CD36 molecule (thrombospondin receptor) |
CD44 | CD44 molecule (Indian blood group) |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CKB | creatine kinase, brain |
CTTN | cortactin |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
DLD | dihydrolipoamide dehydrogenase |
DPT | dermatopontin |
DSP | desmoplakin |
DUSP22 | dual specificity phosphatase 22 |
EGR1 | early growth response 1 |
EMP1 | epithelial membrane protein 1 |
ENO2 | enolase 2 (gamma, neuronal) |
FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
FGG | fibrinogen gamma chain |
FHL1 | four and a half LIM domains 1 |
FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
GADD45A | growth arrest and DNA-damage-inducible, alpha |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GAL | galanin/GMAP prepropeptide |
GEM | GTP binding protein overexpressed in skeletal muscle |
HMOX1 | heme oxygenase 1 |
HSPA1A | heat shock 70kDa protein 1A |
IER5 | immediate early response 5 |
IFI27 | interferon, alpha-inducible protein 27 |
JUN | jun proto-oncogene |
JUNB | jun B proto-oncogene |
KLF10 | Kruppel-like factor 10 |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MMD | monocyte to macrophage differentiation-associated |
MMP1 | matrix metallopeptidase 1 |
ODC1 | ornithine decarboxylase 1 |
P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
RBP1 | retinol binding protein 1, cellular |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SESN1 | sestrin 1 |
SFN | stratifin |
SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
SPON2 | spondin 2, extracellular matrix protein |
STC2 | stanniocalcin 2 |
TFPI2 | tissue factor pathway inhibitor 2 |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
ZNF274 | zinc finger protein 274 |
Symbol | Name |
---|---|
ASF1A | anti-silencing function 1A histone chaperone |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BASP1 | brain abundant, membrane attached signal protein 1 |
BCAS1 | breast carcinoma amplified sequence 1 |
CDH19 | cadherin 19, type 2 |
CDKN2A | cyclin-dependent kinase inhibitor 2A |
CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
DUOX2 | dual oxidase 2 |
EPHA3 | EPH receptor A3 |
ERBB3 | erb-b2 receptor tyrosine kinase 3 |
FAM46A | family with sequence similarity 46, member A |
GPX2 | glutathione peroxidase 2 |
HNMT | histamine N-methyltransferase |
KLHL9 | kelch-like family member 9 |
MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase |
NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
NNMT | nicotinamide N-methyltransferase |
PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
RAB13 | RAB13, member RAS oncogene family |
RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
RHOBTB3 | Rho-related BTB domain containing 3 |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
S100B | S100 calcium binding protein B |
S100P | S100 calcium binding protein P |
SLC38A2 | solute carrier family 38, member 2 |
SMC4 | structural maintenance of chromosomes 4 |
SOX10 | SRY (sex determining region Y)-box 10 |
SULF1 | sulfatase 1 |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TMEM100 | transmembrane protein 100 |
TMEM2 | transmembrane protein 2 |
TNS3 | tensin 3 |
WNT5A | wingless-type MMTV integration site family, member 5A |
XYLT1 | xylosyltransferase I |