| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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156 genes differentially expressed following the BRD-K13390322_AT-7519_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase |
| CAST | calpastatin |
| CD9 | CD9 molecule |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CES1 | carboxylesterase 1 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTSS | cathepsin S |
| CTSZ | cathepsin Z |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DSTN | destrin (actin depolymerizing factor) |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EGR1 | early growth response 1 |
| EMP1 | epithelial membrane protein 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ESRP1 | epithelial splicing regulatory protein 1 |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| FOXF1 | forkhead box F1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GM2A | GM2 ganglioside activator |
| GOLGA8H | golgin A8 family, member H |
| GPNMB | glycoprotein (transmembrane) nmb |
| GSN | gelsolin |
| GSTP1 | glutathione S-transferase pi 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HIST1H4C | histone cluster 1, H4c |
| HLA-B | major histocompatibility complex, class I, B |
| HLA-C | major histocompatibility complex, class I, C |
| HOOK2 | hook microtubule-tethering protein 2 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IER3 | immediate early response 3 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KRT15 | keratin 15, type I |
| KRT6B | keratin 6B, type II |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LDHB | lactate dehydrogenase B |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| LPXN | leupaxin |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| MAOA | monoamine oxidase A |
| MDFIC | MyoD family inhibitor domain containing |
| MGP | matrix Gla protein |
| MMP12 | matrix metallopeptidase 12 |
| MYO6 | myosin VI |
| NAV3 | neuron navigator 3 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NTS | neurotensin |
| OLFM4 | olfactomedin 4 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PER2 | period circadian clock 2 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAUR | plasminogen activator, urokinase receptor |
| PLBD1 | phospholipase B domain containing 1 |
| POSTN | periostin, osteoblast specific factor |
| PRAME | preferentially expressed antigen in melanoma |
| PRR7 | proline rich 7 (synaptic) |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 |
| RAB25 | RAB25, member RAS oncogene family |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCPEP1 | serine carboxypeptidase 1 |
| SESN1 | sestrin 1 |
| SFN | stratifin |
| SFRP1 | secreted frizzled-related protein 1 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| TFF1 | trefoil factor 1 |
| TFF3 | trefoil factor 3 (intestinal) |
| THBS1 | thrombospondin 1 |
| TPBG | trophoblast glycoprotein |
| TPD52 | tumor protein D52 |
| TSPO | translocator protein (18kDa) |
| TUSC3 | tumor suppressor candidate 3 |
| VAMP3 | vesicle-associated membrane protein 3 |
| WIF1 | WNT inhibitory factor 1 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ADCY9 | adenylate cyclase 9 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 |
| ASS1 | argininosuccinate synthase 1 |
| CCNA2 | cyclin A2 |
| CDC25B | cell division cycle 25B |
| CLIC5 | chloride intracellular channel 5 |
| CLU | clusterin |
| DCK | deoxycytidine kinase |
| DCN | decorin |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DPYSL2 | dihydropyrimidinase-like 2 |
| EAPP | E2F-associated phosphoprotein |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| FADS1 | fatty acid desaturase 1 |
| FGB | fibrinogen beta chain |
| FGFR2 | fibroblast growth factor receptor 2 |
| FGG | fibrinogen gamma chain |
| GAS1 | growth arrest-specific 1 |
| GLRX | glutaredoxin (thioltransferase) |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| HSPA8 | heat shock 70kDa protein 8 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IGKV1-5 | immunoglobulin kappa variable 1-5 |
| IL32 | interleukin 32 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA0391 | KIAA0391 |
| L1CAM | L1 cell adhesion molecule |
| LAMA3 | laminin, alpha 3 |
| MMP2 | matrix metallopeptidase 2 |
| MRPL12 | mitochondrial ribosomal protein L12 |
| NDC80 | NDC80 kinetochore complex component |
| NOV | nephroblastoma overexpressed |
| NUP62 | nucleoporin 62kDa |
| ORM1 | orosomucoid 1 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLXNC1 | plexin C1 |
| PNP | purine nucleoside phosphorylase |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma |
| PROM1 | prominin 1 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 |
| RELN | reelin |
| RGS13 | regulator of G-protein signaling 13 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SCAND1 | SCAN domain containing 1 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
| SLC38A2 | solute carrier family 38, member 2 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPTSSA | serine palmitoyltransferase, small subunit A |
| SRP54 | signal recognition particle 54kDa |
| STK10 | serine/threonine kinase 10 |
| TAGLN | transgelin |
| TBP | TATA box binding protein |
| TCF4 | transcription factor 4 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TMEM97 | transmembrane protein 97 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A |
| TNS3 | tensin 3 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TRIM24 | tripartite motif containing 24 |
| TSPYL5 | TSPY-like 5 |
| TXLNA | taxilin alpha |
| USP6NL | USP6 N-terminal like |
| XBP1 | X-box binding protein 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
