BRD-K13390322_AT-7519_LNCAP_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

146 genes differentially expressed following the BRD-K13390322_AT-7519_LNCAP_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AAMDC adipogenesis associated, Mth938 domain containing
ACTA1 actin, alpha 1, skeletal muscle
ADCK3 aarF domain containing kinase 3
AEBP1 AE binding protein 1
AIF1 allograft inflammatory factor 1
AMDHD2 amidohydrolase domain containing 2
ASPN asporin
CD59 CD59 molecule, complement regulatory protein
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
CFB complement factor B
CHPT1 choline phosphotransferase 1
CLIC5 chloride intracellular channel 5
COL6A1 collagen, type VI, alpha 1
CPVL carboxypeptidase, vitellogenic-like
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
EIF5A eukaryotic translation initiation factor 5A
FKBP10 FK506 binding protein 10, 65 kDa
G0S2 G0/G1 switch 2
GOLM1 golgi membrane protein 1
GPM6A glycoprotein M6A
H1F0 H1 histone family, member 0
HACD1 3-hydroxyacyl-CoA dehydratase 1
HBD hemoglobin, delta
IFITM1 interferon induced transmembrane protein 1
IGF1 insulin-like growth factor 1 (somatomedin C)
ITM2C integral membrane protein 2C
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
LAGE3 L antigen family, member 3
LAPTM4B lysosomal protein transmembrane 4 beta
LPL lipoprotein lipase
LXN latexin
MAP7 microtubule-associated protein 7
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCOLCE2 procollagen C-endopeptidase enhancer 2
PPIC peptidylprolyl isomerase C (cyclophilin C)
PXDN peroxidasin
QPRT quinolinate phosphoribosyltransferase
RAB2A RAB2A, member RAS oncogene family
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBKS ribokinase
RPL39L ribosomal protein L39-like
RRAGD Ras-related GTP binding D
S100A7 S100 calcium binding protein A7
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SET SET nuclear proto-oncogene
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SORBS1 sorbin and SH3 domain containing 1
SORT1 sortilin 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPON1 spondin 1, extracellular matrix protein
TIMP3 TIMP metallopeptidase inhibitor 3
TNNC1 troponin C type 1 (slow)
TOR1A torsin family 1, member A (torsin A)
TP53I3 tumor protein p53 inducible protein 3
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TUSC3 tumor suppressor candidate 3
WASF3 WAS protein family, member 3
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ALOX15B arachidonate 15-lipoxygenase, type B
AMIGO2 adhesion molecule with Ig-like domain 2
AUTS2 autism susceptibility candidate 2
BAMBI BMP and activin membrane-bound inhibitor
BASP1 brain abundant, membrane attached signal protein 1
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
CANT1 calcium activated nucleotidase 1
CCNE2 cyclin E2
CCNG2 cyclin G2
CCR7 chemokine (C-C motif) receptor 7
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHIC2 cysteine-rich hydrophobic domain 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSNK1E casein kinase 1, epsilon
CXCL11 chemokine (C-X-C motif) ligand 11
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGR2 early growth response 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FBXO5 F-box protein 5
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GBP1 guanylate binding protein 1, interferon-inducible
GDF15 growth differentiation factor 15
GIMAP4 GTPase, IMAP family member 4
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIC2 hypermethylated in cancer 2
HOPX HOP homeobox
IER2 immediate early response 2
IER5 immediate early response 5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KLF4 Kruppel-like factor 4 (gut)
KRT15 keratin 15, type I
LRIF1 ligand dependent nuclear receptor interacting factor 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAT2A methionine adenosyltransferase II, alpha
MTSS1 metastasis suppressor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
N4BP2L2 NEDD4 binding protein 2-like 2
NAV3 neuron navigator 3
NEFL neurofilament, light polypeptide
NUP153 nucleoporin 153kDa
PEX11A peroxisomal biogenesis factor 11 alpha
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLAGL2 pleiomorphic adenoma gene-like 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POU2AF1 POU class 2 associating factor 1
PRR15L proline rich 15-like
RHOB ras homolog family member B
RIMS3 regulating synaptic membrane exocytosis 3
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERTAD2 SERTA domain containing 2
SESN1 sestrin 1
SGK1 serum/glucocorticoid regulated kinase 1
SNAP25 synaptosomal-associated protein, 25kDa
SOX9 SRY (sex determining region Y)-box 9
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TBP TATA box binding protein
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGIF1 TGFB-induced factor homeobox 1
TMEM243 transmembrane protein 243, mitochondrial
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOB2 transducer of ERBB2, 2
TSC22D3 TSC22 domain family, member 3
TUBA4A tubulin, alpha 4a
VEGFA vascular endothelial growth factor A
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF432 zinc finger protein 432
Funding