| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
155 genes differentially expressed following the BRD-K13390322_AT-7519_MCF7_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACE2 | angiotensin I converting enzyme 2 |
| ADD3 | adducin 3 (gamma) |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| AMT | aminomethyltransferase |
| AQP9 | aquaporin 9 |
| BAG6 | BCL2-associated athanogene 6 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD59 | CD59 molecule, complement regulatory protein |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CES1 | carboxylesterase 1 |
| CFB | complement factor B |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHI3L2 | chitinase 3-like 2 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| COL1A2 | collagen, type I, alpha 2 |
| CPM | carboxypeptidase M |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DCN | decorin |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| EGF | epidermal growth factor |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EIF5A | eukaryotic translation initiation factor 5A |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPCAM | epithelial cell adhesion molecule |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM171A1 | family with sequence similarity 171, member A1 |
| FASN | fatty acid synthase |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| G0S2 | G0/G1 switch 2 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLRX | glutaredoxin (thioltransferase) |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFITM3 | interferon induced transmembrane protein 3 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KIAA0226L | KIAA0226-like |
| LCN2 | lipocalin 2 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MMP9 | matrix metallopeptidase 9 |
| NMU | neuromedin U |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 |
| PENK | proenkephalin |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| QPCT | glutaminyl-peptide cyclotransferase |
| RGS4 | regulator of G-protein signaling 4 |
| S100P | S100 calcium binding protein P |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SDC2 | syndecan 2 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THY1 | Thy-1 cell surface antigen |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| WFDC2 | WAP four-disulfide core domain 2 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| WT1 | Wilms tumor 1 |
| Symbol | Name |
|---|---|
| ADNP | activity-dependent neuroprotector homeobox |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
| AIM1 | absent in melanoma 1 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| AURKA | aurora kinase A |
| BAMBI | BMP and activin membrane-bound inhibitor |
| CCNF | cyclin F |
| CDC25A | cell division cycle 25A |
| CDCA4 | cell division cycle associated 4 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CLU | clusterin |
| COIL | coilin |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP5 | dual specificity phosphatase 5 |
| EFNA1 | ephrin-A1 |
| EGR2 | early growth response 2 |
| ESR1 | estrogen receptor 1 |
| FAM208B | family with sequence similarity 208, member B |
| FHL1 | four and a half LIM domains 1 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GATA3 | GATA binding protein 3 |
| GSPT2 | G1 to S phase transition 2 |
| HOPX | HOP homeobox |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IER5 | immediate early response 5 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| JADE2 | jade family PHD finger 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAT2A | methionine adenosyltransferase II, alpha |
| MED13 | mediator complex subunit 13 |
| MREG | melanoregulin |
| MT1H | metallothionein 1H |
| MT1X | metallothionein 1X |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| NET1 | neuroepithelial cell transforming 1 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NOL11 | nucleolar protein 11 |
| NOTCH2 | notch 2 |
| NRIP1 | nuclear receptor interacting protein 1 |
| NUP62 | nucleoporin 62kDa |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLAC8 | placenta-specific 8 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D |
| PRPF4 | pre-mRNA processing factor 4 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RBM47 | RNA binding motif protein 47 |
| RHOB | ras homolog family member B |
| RND3 | Rho family GTPase 3 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERTAD2 | SERTA domain containing 2 |
| SESN1 | sestrin 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SMG8 | SMG8 nonsense mediated mRNA decay factor |
| SNX11 | sorting nexin 11 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TBP | TATA box binding protein |
| TBPL1 | TBP-like 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TFF1 | trefoil factor 1 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNPO1 | transportin 1 |
| TOB1 | transducer of ERBB2, 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TUBD1 | tubulin, delta 1 |
| UMPS | uridine monophosphate synthetase |
| USP1 | ubiquitin specific peptidase 1 |
| VEZF1 | vascular endothelial zinc finger 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF217 | zinc finger protein 217 |
