BRD-K13533483_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-K13533483_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA5 annexin A5
ARF4 ADP-ribosylation factor 4
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CREB3L2 cAMP responsive element binding protein 3-like 2
CRELD2 cysteine-rich with EGF-like domains 2
CYB561 cytochrome b561
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
FKBP11 FK506 binding protein 11, 19 kDa
FKBP14 FK506 binding protein 14, 22 kDa
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLRX glutaredoxin (thioltransferase)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HYOU1 hypoxia up-regulated 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
ISG15 ISG15 ubiquitin-like modifier
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LDLR low density lipoprotein receptor
MANF mesencephalic astrocyte-derived neurotrophic factor
MIA3 melanoma inhibitory activity family, member 3
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NANS N-acetylneuraminic acid synthase
NUCB2 nucleobindin 2
P4HB prolyl 4-hydroxylase, beta polypeptide
PDIA3 protein disulfide isomerase family A, member 3
PDIA4 protein disulfide isomerase family A, member 4
PGM3 phosphoglucomutase 3
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RPS11 ribosomal protein S11
S100A11 S100 calcium binding protein A11
SDF2L1 stromal cell-derived factor 2-like 1
SEC24A SEC24 family member A
SEC24D SEC24 family member D
SEC31A SEC31 homolog A (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SERP1 stress-associated endoplasmic reticulum protein 1
SFRP4 secreted frizzled-related protein 4
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC35B1 solute carrier family 35, member B1
SRPR signal recognition particle receptor (docking protein)
SRPRB signal recognition particle receptor, B subunit
SSR1 signal sequence receptor, alpha
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM39A transmembrane protein 39A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNT1 troponin T type 1 (skeletal, slow)
TXNIP thioredoxin interacting protein
TXNL4B thioredoxin-like 4B
UFM1 ubiquitin-fold modifier 1
WFS1 Wolfram syndrome 1 (wolframin)
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ADM adrenomedullin
AREG amphiregulin
CA2 carbonic anhydrase II
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CCND1 cyclin D1
CD69 CD69 molecule
CHN1 chimerin 1
CKB creatine kinase, brain
CNN3 calponin 3, acidic
CXCL9 chemokine (C-X-C motif) ligand 9
EPAS1 endothelial PAS domain protein 1
GJA1 gap junction protein, alpha 1, 43kDa
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
KLK10 kallikrein-related peptidase 10
LAMP3 lysosomal-associated membrane protein 3
NELL2 NEL-like 2 (chicken)
PDE4B phosphodiesterase 4B, cAMP-specific
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RCAN2 regulator of calcineurin 2
RTN1 reticulon 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9