BRD-K13566078_BMS-345541_MCF7_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K13566078_BMS-345541_MCF7_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CXCR4 chemokine (C-X-C motif) receptor 4
DDAH1 dimethylarginine dimethylaminohydrolase 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPCAM epithelial cell adhesion molecule
FBP1 fructose-1,6-bisphosphatase 1
FN1 fibronectin 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHM immunoglobulin heavy constant mu
IL13RA2 interleukin 13 receptor, alpha 2
IL7R interleukin 7 receptor
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
LGALS4 lectin, galactoside-binding, soluble, 4
MAMLD1 mastermind-like domain containing 1
MXRA5 matrix-remodelling associated 5
NEBL nebulette
RGS2 regulator of G-protein signaling 2
RHOBTB3 Rho-related BTB domain containing 3
RRAS2 related RAS viral (r-ras) oncogene homolog 2
TM9SF3 transmembrane 9 superfamily member 3
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACKR3 atypical chemokine receptor 3
AGR2 anterior gradient 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHNAK2 AHNAK nucleoprotein 2
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
AQP3 aquaporin 3 (Gill blood group)
C2CD2 C2 calcium-dependent domain containing 2
CA12 carbonic anhydrase XII
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CXCL5 chemokine (C-X-C motif) ligand 5
FABP4 fatty acid binding protein 4, adipocyte
FCGBP Fc fragment of IgG binding protein
FZD6 frizzled class receptor 6
IGFBP5 insulin-like growth factor binding protein 5
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JADE2 jade family PHD finger 2
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRT4 keratin 4, type II
KRT7 keratin 7, type II
LCN2 lipocalin 2
LOC100505650 uncharacterized LOC100505650
NRN1 neuritin 1
PFKP phosphofructokinase, platelet
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PPL periplakin
PTPRK protein tyrosine phosphatase, receptor type, K
PXDN peroxidasin
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBPMS RNA binding protein with multiple splicing
SLPI secretory leukocyte peptidase inhibitor
SNAP25 synaptosomal-associated protein, 25kDa
SPAG4 sperm associated antigen 4
SPARCL1 SPARC-like 1 (hevin)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPP1 secreted phosphoprotein 1
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
UPK1B uroplakin 1B
Funding