| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
108 genes differentially expressed following the BRD-K13646352_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ALCAM | activated leukocyte cell adhesion molecule |
| ANPEP | alanyl (membrane) aminopeptidase |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| BCL6 | B-cell CLL/lymphoma 6 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DHCR7 | 7-dehydrocholesterol reductase |
| DUSP1 | dual specificity phosphatase 1 |
| FKBP11 | FK506 binding protein 11, 19 kDa |
| GAB2 | GRB2-associated binding protein 2 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IRF4 | interferon regulatory factor 4 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LONP2 | lon peptidase 2, peroxisomal |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| MCOLN1 | mucolipin 1 |
| NEFM | neurofilament, medium polypeptide |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NNMT | nicotinamide N-methyltransferase |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PCP4 | Purkinje cell protein 4 |
| PON3 | paraoxonase 3 |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| PRSS21 | protease, serine, 21 (testisin) |
| PSAT1 | phosphoserine aminotransferase 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
| SRGN | serglycin |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TCF4 | transcription factor 4 |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TES | testin LIM domain protein |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| THY1 | Thy-1 cell surface antigen |
| TPBG | trophoblast glycoprotein |
| TUSC3 | tumor suppressor candidate 3 |
| TXNIP | thioredoxin interacting protein |
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 |
| BAG3 | BCL2-associated athanogene 3 |
| BMP2 | bone morphogenetic protein 2 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CCNB1 | cyclin B1 |
| CCNE2 | cyclin E2 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CLDN4 | claudin 4 |
| CTSW | cathepsin W |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CYCS | cytochrome c, somatic |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EPHA3 | EPH receptor A3 |
| FYB | FYN binding protein |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GDF15 | growth differentiation factor 15 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| H3F3B | H3 histone, family 3B (H3.3B) |
| HDAC9 | histone deacetylase 9 |
| HOMER1 | homer scaffolding protein 1 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPB8 | heat shock 22kDa protein 8 |
| IL32 | interleukin 32 |
| IL7R | interleukin 7 receptor |
| IPO13 | importin 13 |
| JAG1 | jagged 1 |
| JMJD6 | jumonji domain containing 6 |
| KLHL21 | kelch-like family member 21 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
| MGP | matrix Gla protein |
| MMP12 | matrix metallopeptidase 12 |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| PDLIM3 | PDZ and LIM domain 3 |
| PGBD5 | piggyBac transposable element derived 5 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform |
| PRDX2 | peroxiredoxin 2 |
| RHOB | ras homolog family member B |
| RPIA | ribose 5-phosphate isomerase A |
| SATB2 | SATB homeobox 2 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SMAD7 | SMAD family member 7 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| TGFA | transforming growth factor, alpha |
| THBS4 | thrombospondin 4 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TOX3 | TOX high mobility group box family member 3 |
| VAMP8 | vesicle-associated membrane protein 8 |
| VLDLR | very low density lipoprotein receptor |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
