| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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141 genes differentially expressed following the BRD-K13662825_dinaciclib_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| ANOS1 | anosmin 1 |
| ARHGAP32 | Rho GTPase activating protein 32 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| CD8A | CD8a molecule |
| CFD | complement factor D (adipsin) |
| COL1A1 | collagen, type I, alpha 1 |
| COLEC12 | collectin sub-family member 12 |
| CSTA | cystatin A (stefin A) |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| CYBA | cytochrome b-245, alpha polypeptide |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DICER1 | dicer 1, ribonuclease type III |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DSE | dermatan sulfate epimerase |
| EGFL6 | EGF-like-domain, multiple 6 |
| EGR1 | early growth response 1 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ETV1 | ets variant 1 |
| FAM20B | family with sequence similarity 20, member B |
| FGFR3 | fibroblast growth factor receptor 3 |
| FGL2 | fibrinogen-like 2 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H4H | histone cluster 1, H4h |
| HSPB8 | heat shock 22kDa protein 8 |
| IER3 | immediate early response 3 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGKV4-1 | immunoglobulin kappa variable 4-1 |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| ITM2A | integral membrane protein 2A |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KRT19 | keratin 19, type I |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LOC100272216 | uncharacterized LOC100272216 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| METRN | meteorin, glial cell differentiation regulator |
| NEBL | nebulette |
| NGRN | neugrin, neurite outgrowth associated |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NTS | neurotensin |
| OLFM1 | olfactomedin 1 |
| PRF1 | perforin 1 (pore forming protein) |
| PRR7 | proline rich 7 (synaptic) |
| PTPRC | protein tyrosine phosphatase, receptor type, C |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SFTPC | surfactant protein C |
| SIK1 | salt-inducible kinase 1 |
| STC1 | stanniocalcin 1 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TMEM164 | transmembrane protein 164 |
| TRBC1 | T cell receptor beta constant 1 |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 |
| ZNF131 | zinc finger protein 131 |
| ZNF331 | zinc finger protein 331 |
| Symbol | Name |
|---|---|
| ARFIP2 | ADP-ribosylation factor interacting protein 2 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| CCNA2 | cyclin A2 |
| CD24 | CD24 molecule |
| CDC20 | cell division cycle 20 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CENPU | centromere protein U |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CTBP2 | C-terminal binding protein 2 |
| DCK | deoxycytidine kinase |
| DERA | deoxyribose-phosphate aldolase (putative) |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FHL2 | four and a half LIM domains 2 |
| FOXO1 | forkhead box O1 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXA10 | homeobox A10 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| JMJD6 | jumonji domain containing 6 |
| KLK10 | kallikrein-related peptidase 10 |
| KRT14 | keratin 14, type I |
| LDLR | low density lipoprotein receptor |
| LIMS1 | LIM and senescent cell antigen-like domains 1 |
| LTF | lactotransferrin |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MSMO1 | methylsterol monooxygenase 1 |
| MTSS1 | metastasis suppressor 1 |
| NFIB | nuclear factor I/B |
| NUP62 | nucleoporin 62kDa |
| NXN | nucleoredoxin |
| PAPD7 | PAP associated domain containing 7 |
| PARP2 | poly (ADP-ribose) polymerase 2 |
| PAX8 | paired box 8 |
| PEG10 | paternally expressed 10 |
| PFKP | phosphofructokinase, platelet |
| PLK1 | polo-like kinase 1 |
| PNP | purine nucleoside phosphorylase |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region |
| RGCC | regulator of cell cycle |
| RNPS1 | RNA binding protein S1, serine-rich domain |
| S100A8 | S100 calcium binding protein A8 |
| SLBP | stem-loop binding protein |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| TCF4 | transcription factor 4 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TM9SF3 | transmembrane 9 superfamily member 3 |
| TUBA4A | tubulin, alpha 4a |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB3 | tubulin, beta 3 class III |
| TXLNA | taxilin alpha |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| USP1 | ubiquitin specific peptidase 1 |
| USP22 | ubiquitin specific peptidase 22 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
