| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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175 genes differentially expressed following the BRD-K13662825_dinaciclib_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADCK3 | aarF domain containing kinase 3 |
| ADD3 | adducin 3 (gamma) |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AHR | aryl hydrocarbon receptor |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AQP1 | aquaporin 1 (Colton blood group) |
| AREG | amphiregulin |
| ARL3 | ADP-ribosylation factor-like 3 |
| BLNK | B-cell linker |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| BZW2 | basic leucine zipper and W2 domains 2 |
| CADM1 | cell adhesion molecule 1 |
| CALD1 | caldesmon 1 |
| CD302 | CD302 molecule |
| CD4 | CD4 molecule |
| CD46 | CD46 molecule, complement regulatory protein |
| CETN2 | centrin, EF-hand protein, 2 |
| CFB | complement factor B |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CKB | creatine kinase, brain |
| CLU | clusterin |
| COL11A1 | collagen, type XI, alpha 1 |
| CRISP3 | cysteine-rich secretory protein 3 |
| CTSO | cathepsin O |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DCTD | dCMP deaminase |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DSE | dermatan sulfate epimerase |
| DST | dystonin |
| EGR1 | early growth response 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FAM149A | family with sequence similarity 149, member A |
| FGFR3 | fibroblast growth factor receptor 3 |
| FHL1 | four and a half LIM domains 1 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) |
| FMO3 | flavin containing monooxygenase 3 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOXF1 | forkhead box F1 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GLIPR1 | GLI pathogenesis-related 1 |
| GPM6A | glycoprotein M6A |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPX3 | glutathione peroxidase 3 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| HBB | hemoglobin, beta |
| HBD | hemoglobin, delta |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| IL1R1 | interleukin 1 receptor, type I |
| IL6 | interleukin 6 |
| IL7R | interleukin 7 receptor |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAOA | monoamine oxidase A |
| MDFIC | MyoD family inhibitor domain containing |
| METTL7A | methyltransferase like 7A |
| NDUFA4 | NDUFA4, mitochondrial complex associated |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PCBP2 | poly(rC) binding protein 2 |
| PDGFC | platelet derived growth factor C |
| PHACTR2 | phosphatase and actin regulator 2 |
| PLXNB2 | plexin B2 |
| RASA4 | RAS p21 protein activator 4 |
| RHOB | ras homolog family member B |
| SCARB2 | scavenger receptor class B, member 2 |
| SCP2 | sterol carrier protein 2 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC16A4 | solute carrier family 16, member 4 |
| SPP1 | secreted phosphoprotein 1 |
| STC1 | stanniocalcin 1 |
| SYT1 | synaptotagmin I |
| TBX2 | T-box 2 |
| TCTN1 | tectonic family member 1 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMEM47 | transmembrane protein 47 |
| TXNIP | thioredoxin interacting protein |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| WIF1 | WNT inhibitory factor 1 |
| Symbol | Name |
|---|---|
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ACBD3 | acyl-CoA binding domain containing 3 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BAG3 | BCL2-associated athanogene 3 |
| BAG5 | BCL2-associated athanogene 5 |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BLCAP | bladder cancer associated protein |
| CALML5 | calmodulin-like 5 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CDC20 | cell division cycle 20 |
| CDC25B | cell division cycle 25B |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EIF5 | eukaryotic translation initiation factor 5 |
| FHL2 | four and a half LIM domains 2 |
| FOSL1 | FOS-like antigen 1 |
| FOXJ3 | forkhead box J3 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GDF15 | growth differentiation factor 15 |
| GTPBP8 | GTP-binding protein 8 (putative) |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L |
| HOXA10 | homeobox A10 |
| HOXB7 | homeobox B7 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGA6 | integrin, alpha 6 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIAA0101 | KIAA0101 |
| KLK11 | kallikrein-related peptidase 11 |
| KRT14 | keratin 14, type I |
| KRT15 | keratin 15, type I |
| KRT17 | keratin 17, type I |
| KRT23 | keratin 23, type I |
| KRT6B | keratin 6B, type II |
| KRT7 | keratin 7, type II |
| LDLR | low density lipoprotein receptor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
| MLPH | melanophilin |
| MRPS2 | mitochondrial ribosomal protein S2 |
| MYBPC1 | myosin binding protein C, slow type |
| NES | nestin |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NRN1 | neuritin 1 |
| NUP62 | nucleoporin 62kDa |
| PLAC8 | placenta-specific 8 |
| PMM2 | phosphomannomutase 2 |
| PNP | purine nucleoside phosphorylase |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PUF60 | poly-U binding splicing factor 60KDa |
| RAE1 | ribonucleic acid export 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RIN2 | Ras and Rab interactor 2 |
| S100P | S100 calcium binding protein P |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| SYNM | synemin, intermediate filament protein |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TRAPPC3 | trafficking protein particle complex 3 |
| TSPYL5 | TSPY-like 5 |
| TXLNA | taxilin alpha |
| TXNRD1 | thioredoxin reductase 1 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| USP22 | ubiquitin specific peptidase 22 |
| VGLL4 | vestigial-like family member 4 |
| WEE1 | WEE1 G2 checkpoint kinase |
| YBX3 | Y box binding protein 3 |
