| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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125 genes differentially expressed following the BRD-K14109347_LY2603618_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| ARHGAP29 | Rho GTPase activating protein 29 |
| ARL4A | ADP-ribosylation factor-like 4A |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ATF3 | activating transcription factor 3 |
| C3ORF14 | chromosome 3 open reading frame 14 |
| CCNL1 | cyclin L1 |
| CDC20 | cell division cycle 20 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CGRRF1 | cell growth regulator with ring finger domain 1 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CLGN | calmegin |
| COCH | cochlin |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYB5R1 | cytochrome b5 reductase 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| EIF5 | eukaryotic translation initiation factor 5 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GDF15 | growth differentiation factor 15 |
| HIST1H4J | histone cluster 1, H4j |
| HIST3H2A | histone cluster 3, H2a |
| HOXD1 | homeobox D1 |
| IER5 | immediate early response 5 |
| IQCG | IQ motif containing G |
| KIAA0907 | KIAA0907 |
| MICB | MHC class I polypeptide-related sequence B |
| MLF1 | myeloid leukemia factor 1 |
| MYBPC1 | myosin binding protein C, slow type |
| NEK2 | NIMA-related kinase 2 |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NPY | neuropeptide Y |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNP | purine nucleoside phosphorylase |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma |
| RAD9A | RAD9 homolog A (S. pombe) |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS2 | regulator of G-protein signaling 2 |
| RHOB | ras homolog family member B |
| SQSTM1 | sequestosome 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| STK17A | serine/threonine kinase 17a |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TESC | tescalcin |
| TSC22D3 | TSC22 domain family, member 3 |
| TUBB2A | tubulin, beta 2A class IIa |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| Symbol | Name |
|---|---|
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa |
| ATP5C1 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| ATP9A | ATPase, class II, type 9A |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 |
| CCND2 | cyclin D2 |
| CD200 | CD200 molecule |
| CERS6 | ceramide synthase 6 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EDNRB | endothelin receptor type B |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| IQGAP1 | IQ motif containing GTPase activating protein 1 |
| IRF8 | interferon regulatory factor 8 |
| ITGA6 | integrin, alpha 6 |
| KIF5B | kinesin family member 5B |
| LOX | lysyl oxidase |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MAGEA3 | melanoma antigen family A3 |
| MEIS1 | Meis homeobox 1 |
| MMP12 | matrix metallopeptidase 12 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MYH10 | myosin, heavy chain 10, non-muscle |
| NEBL | nebulette |
| NRCAM | neuronal cell adhesion molecule |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PFKP | phosphofructokinase, platelet |
| PGAM1 | phosphoglycerate mutase 1 (brain) |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PKP4 | plakophilin 4 |
| PLBD1 | phospholipase B domain containing 1 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PRAME | preferentially expressed antigen in melanoma |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PRKCA | protein kinase C, alpha |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| RBL2 | retinoblastoma-like 2 |
| RGS5 | regulator of G-protein signaling 5 |
| SCARB2 | scavenger receptor class B, member 2 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SVIL | supervillin |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TKT | transketolase |
| TMEM47 | transmembrane protein 47 |
| TRAK2 | trafficking protein, kinesin binding 2 |
| TRIM2 | tripartite motif containing 2 |
| VDAC1 | voltage-dependent anion channel 1 |
| WAC | WW domain containing adaptor with coiled-coil |
| ZMYND11 | zinc finger, MYND-type containing 11 |
