BRD-K14441456_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K14441456_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AMIGO2 adhesion molecule with Ig-like domain 2
CALR calreticulin
DDIT3 DNA-damage-inducible transcript 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
GJA1 gap junction protein, alpha 1, 43kDa
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA13 heat shock protein 70kDa family, member 13
HYOU1 hypoxia up-regulated 1
IGKC immunoglobulin kappa constant
IL1R1 interleukin 1 receptor, type I
LGALS3 lectin, galactoside-binding, soluble, 3
MANF mesencephalic astrocyte-derived neurotrophic factor
MAT2A methionine adenosyltransferase II, alpha
NKX3-1 NK3 homeobox 1
NRG1 neuregulin 1
NTS neurotensin
NUCB2 nucleobindin 2
PDIA4 protein disulfide isomerase family A, member 4
RPL37A ribosomal protein L37a
SDF2L1 stromal cell-derived factor 2-like 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STAR steroidogenic acute regulatory protein
VEGFA vascular endothelial growth factor A
VIM vimentin

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EGFL6 EGF-like-domain, multiple 6
FBLN1 fibulin 1
GAS1 growth arrest-specific 1
MECOM MDS1 and EVI1 complex locus
MEIS1 Meis homeobox 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RHOBTB3 Rho-related BTB domain containing 3
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A8 S100 calcium binding protein A8
SORBS1 sorbin and SH3 domain containing 1
Funding