BRD-K14609189_3-(5-{[3-(4-methoxy-2-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)propanoic acid_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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26 genes differentially expressed following the BRD-K14609189_3-(5-{[3-(4-methoxy-2-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)propanoic acid_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CD24 CD24 molecule
CD9 CD9 molecule
CEP57 centrosomal protein 57kDa
FHL1 four and a half LIM domains 1
IPO13 importin 13
MYL2 myosin, light chain 2, regulatory, cardiac, slow
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
SFN stratifin
SULF1 sulfatase 1
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CLEC2B C-type lectin domain family 2, member B
DHRS2 dehydrogenase/reductase (SDR family) member 2
DUSP4 dual specificity phosphatase 4
HOXA10 homeobox A10
LGALS3 lectin, galactoside-binding, soluble, 3
NRN1 neuritin 1
RGS2 regulator of G-protein signaling 2