| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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158 genes differentially expressed following the BRD-K14618467_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| ACKR3 | atypical chemokine receptor 3 |
| ADIRF | adipogenesis regulatory factor |
| APOA1 | apolipoprotein A-I |
| ARF1 | ADP-ribosylation factor 1 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CCNG2 | cyclin G2 |
| CD24 | CD24 molecule |
| CD99 | CD99 molecule |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CETN2 | centrin, EF-hand protein, 2 |
| CLGN | calmegin |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 |
| CRIP2 | cysteine-rich protein 2 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
| DAZAP2 | DAZ associated protein 2 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHCR24 | 24-dehydrocholesterol reductase |
| DHCR7 | 7-dehydrocholesterol reductase |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DPP4 | dipeptidyl-peptidase 4 |
| EBP | emopamil binding protein (sterol isomerase) |
| FADS1 | fatty acid desaturase 1 |
| FADS2 | fatty acid desaturase 2 |
| FASN | fatty acid synthase |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FHL1 | four and a half LIM domains 1 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HBP1 | HMG-box transcription factor 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2BD | histone cluster 1, H2bd |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| INSIG1 | insulin induced gene 1 |
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 |
| LDLR | low density lipoprotein receptor |
| LPIN1 | lipin 1 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| METTL7A | methyltransferase like 7A |
| MICB | MHC class I polypeptide-related sequence B |
| MSMO1 | methylsterol monooxygenase 1 |
| MT1F | metallothionein 1F |
| MXI1 | MAX interactor 1, dimerization protein |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSR2 | odd-skipped related transciption factor 2 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 |
| PDGFRL | platelet-derived growth factor receptor-like |
| PER1 | period circadian clock 1 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| QPRT | quinolinate phosphoribosyltransferase |
| RAD9A | RAD9 homolog A (S. pombe) |
| RPS27L | ribosomal protein S27-like |
| RRAGD | Ras-related GTP binding D |
| SARAF | store-operated calcium entry-associated regulatory factor |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SCPEP1 | serine carboxypeptidase 1 |
| SEC61B | Sec61 beta subunit |
| SQLE | squalene epoxidase |
| SQSTM1 | sequestosome 1 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| SSR4 | signal sequence receptor, delta |
| THBS2 | thrombospondin 2 |
| TMSB15A | thymosin beta 15a |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TOB1 | transducer of ERBB2, 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| TUBA1A | tubulin, alpha 1a |
| TXNIP | thioredoxin interacting protein |
| VEGFA | vascular endothelial growth factor A |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
| ACTN1 | actinin, alpha 1 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
| ADORA2B | adenosine A2b receptor |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BTBD3 | BTB (POZ) domain containing 3 |
| CA2 | carbonic anhydrase II |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDC25A | cell division cycle 25A |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CKLF | chemokine-like factor |
| CSK | c-src tyrosine kinase |
| CTSZ | cathepsin Z |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| DUSP7 | dual specificity phosphatase 7 |
| EED | embryonic ectoderm development |
| EGR3 | early growth response 3 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EPHA2 | EPH receptor A2 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM57A | family with sequence similarity 57, member A |
| FHL2 | four and a half LIM domains 2 |
| FOSL1 | FOS-like antigen 1 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
| GATA2 | GATA binding protein 2 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| HOMER1 | homer scaffolding protein 1 |
| IER3 | immediate early response 3 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KRT17 | keratin 17, type I |
| MAT2A | methionine adenosyltransferase II, alpha |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MSH6 | mutS homolog 6 |
| MTCL1 | microtubule crosslinking factor 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NOP16 | NOP16 nucleolar protein |
| NUP62 | nucleoporin 62kDa |
| PCNA | proliferating cell nuclear antigen |
| PDCD2 | programmed cell death 2 |
| PI3 | peptidase inhibitor 3, skin-derived |
| PLAC8 | placenta-specific 8 |
| PLK2 | polo-like kinase 2 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRKCA | protein kinase C, alpha |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RGS2 | regulator of G-protein signaling 2 |
| RRP1B | ribosomal RNA processing 1B |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A2 | S100 calcium binding protein A2 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SFN | stratifin |
| SNAI2 | snail family zinc finger 2 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRGN | serglycin |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TRAPPC4 | trafficking protein particle complex 4 |
| TSPAN8 | tetraspanin 8 |
| WDR3 | WD repeat domain 3 |
