BRD-K14765469_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K14765469_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACPP acid phosphatase, prostate
BMP4 bone morphogenetic protein 4
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CNN1 calponin 1, basic, smooth muscle
CRABP2 cellular retinoic acid binding protein 2
ERBB4 erb-b2 receptor tyrosine kinase 4
FAM129A family with sequence similarity 129, member A
FAM69A family with sequence similarity 69, member A
FHL1 four and a half LIM domains 1
IPO13 importin 13
LMOD1 leiomodin 1 (smooth muscle)
PCP4 Purkinje cell protein 4
PMM2 phosphomannomutase 2
S100A8 S100 calcium binding protein A8
SCUBE2 signal peptide, CUB domain, EGF-like 2
SSPN sarcospan
SULF1 sulfatase 1
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
CHPT1 choline phosphotransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
EIF5A eukaryotic translation initiation factor 5A
FABP5 fatty acid binding protein 5 (psoriasis-associated)
LAPTM4B lysosomal protein transmembrane 4 beta
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
S100A2 S100 calcium binding protein A2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLIRP SRA stem-loop interacting RNA binding protein
TRIP6 thyroid hormone receptor interactor 6
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2S ubiquitin-conjugating enzyme E2S