BRD-K14788918_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

69 genes differentially expressed following the BRD-K14788918_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
ALDOC aldolase C, fructose-bisphosphate
ASNS asparagine synthetase (glutamine-hydrolyzing)
AUTS2 autism susceptibility candidate 2
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CCND2 cyclin D2
CHIC2 cysteine-rich hydrophobic domain 2
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
ENO2 enolase 2 (gamma, neuronal)
F3 coagulation factor III (thromboplastin, tissue factor)
FAM162A family with sequence similarity 162, member A
GBE1 glucan (1,4-alpha-), branching enzyme 1
GLRX glutaredoxin (thioltransferase)
GOLGA8A golgin A8 family, member A
GPI glucose-6-phosphate isomerase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HK2 hexokinase 2
IGFBP3 insulin-like growth factor binding protein 3
KDM3A lysine (K)-specific demethylase 3A
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDRG1 N-myc downstream regulated 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
ODC1 ornithine decarboxylase 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKP phosphofructokinase, platelet
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PHGDH phosphoglycerate dehydrogenase
PLAT plasminogen activator, tissue
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNMA2 paraneoplastic Ma antigen 2
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RGS2 regulator of G-protein signaling 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SRSF6 serine/arginine-rich splicing factor 6
STXBP1 syntaxin binding protein 1
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UFM1 ubiquitin-fold modifier 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AURKA aurora kinase A
CCNF cyclin F
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
GREB1 growth regulation by estrogen in breast cancer 1
HIST1H2BD histone cluster 1, H2bd
HSPA1A heat shock 70kDa protein 1A
KIF20A kinesin family member 20A
MEIS1 Meis homeobox 1
MTSS1 metastasis suppressor 1
PEG10 paternally expressed 10
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21