BRD-K14788918_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

102 genes differentially expressed following the BRD-K14788918_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
AK4 adenylate kinase 4
AKAP12 A kinase (PRKA) anchor protein 12
ALDOA aldolase A, fructose-bisphosphate
ALDOC aldolase C, fructose-bisphosphate
ANO1 anoctamin 1, calcium activated chloride channel
ASNS asparagine synthetase (glutamine-hydrolyzing)
BEX1 brain expressed, X-linked 1
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG1 B-cell translocation gene 1, anti-proliferative
CA2 carbonic anhydrase II
CCNE2 cyclin E2
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CP ceruloplasmin (ferroxidase)
CSRP2 cysteine and glycine-rich protein 2
DARS aspartyl-tRNA synthetase
DDIT4 DNA-damage-inducible transcript 4
EGLN3 egl-9 family hypoxia-inducible factor 3
ENO2 enolase 2 (gamma, neuronal)
FAM57A family with sequence similarity 57, member A
G0S2 G0/G1 switch 2
GBE1 glucan (1,4-alpha-), branching enzyme 1
GLRX glutaredoxin (thioltransferase)
GOLGA8A golgin A8 family, member A
GPI glucose-6-phosphate isomerase
GSAP gamma-secretase activating protein
HCAR3 hydroxycarboxylic acid receptor 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HK2 hexokinase 2
HMOX1 heme oxygenase 1
IFITM1 interferon induced transmembrane protein 1
IL32 interleukin 32
IQCG IQ motif containing G
KDM3A lysine (K)-specific demethylase 3A
KLF4 Kruppel-like factor 4 (gut)
LOXL2 lysyl oxidase-like 2
LRP4 low density lipoprotein receptor-related protein 4
MAP1B microtubule-associated protein 1B
MMP12 matrix metallopeptidase 12
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MUC5B mucin 5B, oligomeric mucus/gel-forming
MXI1 MAX interactor 1, dimerization protein
NAMPT nicotinamide phosphoribosyltransferase
NDRG1 N-myc downstream regulated 1
NRN1 neuritin 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PLAC8 placenta-specific 8
PLBD1 phospholipase B domain containing 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
RNASET2 ribonuclease T2
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCYL3 SCY1-like 3 (S. cerevisiae)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC38A1 solute carrier family 38, member 1
SPAG4 sperm associated antigen 4
STC1 stanniocalcin 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SYBU syntabulin (syntaxin-interacting)
TF transferrin
TGFA transforming growth factor, alpha
TMEM45A transmembrane protein 45A
TSC22D3 TSC22 domain family, member 3
TSPAN8 tetraspanin 8
VEGFA vascular endothelial growth factor A
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
AURKA aurora kinase A
CCNF cyclin F
CD36 CD36 molecule (thrombospondin receptor)
CDKN2A cyclin-dependent kinase inhibitor 2A
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP4 fatty acid binding protein 4, adipocyte
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HIST1H1C histone cluster 1, H1c
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
LXN latexin
MAP7 microtubule-associated protein 7
TFPI2 tissue factor pathway inhibitor 2
ZNF331 zinc finger protein 331