BRD-K14888893_minoxidil_SW620_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

94 genes differentially expressed following the BRD-K14888893_minoxidil_SW620_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ATF1 activating transcription factor 1
CCND2 cyclin D2
CD47 CD47 molecule
CHEK1 checkpoint kinase 1
CLDND1 claudin domain containing 1
CLIC4 chloride intracellular channel 4
CRYZ crystallin, zeta (quinone reductase)
DLD dihydrolipoamide dehydrogenase
DSP desmoplakin
EGR3 early growth response 3
FASTKD5 FAST kinase domains 5
FGFR3 fibroblast growth factor receptor 3
GBP1 guanylate binding protein 1, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
HACD2 3-hydroxyacyl-CoA dehydratase 2
HDGFRP3 hepatoma-derived growth factor, related protein 3
HOPX HOP homeobox
LUM lumican
LYPLA1 lysophospholipase I
MBNL2 muscleblind-like splicing regulator 2
NLRP2 NLR family, pyrin domain containing 2
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PLS3 plastin 3
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PRNP prion protein
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTGER3 prostaglandin E receptor 3 (subtype EP3)
S100A13 S100 calcium binding protein A13
SDC1 syndecan 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTSSA serine palmitoyltransferase, small subunit A
SST somatostatin
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE3C ubiquitin protein ligase E3C

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
AKR1C2 aldo-keto reductase family 1, member C2
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5 arachidonate 5-lipoxygenase
ANPEP alanyl (membrane) aminopeptidase
AQP3 aquaporin 3 (Gill blood group)
ASCL1 achaete-scute family bHLH transcription factor 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL6 B-cell CLL/lymphoma 6
CD163 CD163 molecule
CDK6 cyclin-dependent kinase 6
CHN2 chimerin 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CNR1 cannabinoid receptor 1 (brain)
COTL1 coactosin-like F-actin binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
FADS1 fatty acid desaturase 1
FAM46A family with sequence similarity 46, member A
FZD10 frizzled class receptor 10
GPX3 glutathione peroxidase 3
HCK HCK proto-oncogene, Src family tyrosine kinase
HIST1H4C histone cluster 1, H4c
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL1R1 interleukin 1 receptor, type I
IL7R interleukin 7 receptor
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KPNA6 karyopherin alpha 6 (importin alpha 7)
KRT23 keratin 23, type I
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MT1M metallothionein 1M
NAV3 neuron navigator 3
NFIB nuclear factor I/B
NQO1 NAD(P)H dehydrogenase, quinone 1
PGLS 6-phosphogluconolactonase
PRR7 proline rich 7 (synaptic)
RELN reelin
RHOBTB3 Rho-related BTB domain containing 3
SCGB1D2 secretoglobin, family 1D, member 2
SDC2 syndecan 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIDT2 SID1 transmembrane family, member 2
SLC38A1 solute carrier family 38, member 1
SLC44A4 solute carrier family 44, member 4
STC1 stanniocalcin 1
TFF3 trefoil factor 3 (intestinal)
TGFA transforming growth factor, alpha
TGOLN2 trans-golgi network protein 2
TRIB2 tribbles pseudokinase 2
ZBTB16 zinc finger and BTB domain containing 16
ZIC1 Zic family member 1
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF652 zinc finger protein 652
ZNF91 zinc finger protein 91
Funding