Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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92 genes differentially expressed following the BRD-K15025317_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABHD4 | abhydrolase domain containing 4 |
ACP5 | acid phosphatase 5, tartrate resistant |
AKAP12 | A kinase (PRKA) anchor protein 12 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
ANPEP | alanyl (membrane) aminopeptidase |
BLVRB | biliverdin reductase B |
CCL13 | chemokine (C-C motif) ligand 13 |
CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
CD52 | CD52 molecule |
CNPY3 | canopy FGF signaling regulator 3 |
CTSB | cathepsin B |
DDIT3 | DNA-damage-inducible transcript 3 |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
EMC3 | ER membrane protein complex subunit 3 |
FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
FCMR | Fc fragment of IgM receptor |
FTH1 | ferritin, heavy polypeptide 1 |
G6PD | glucose-6-phosphate dehydrogenase |
GCLC | glutamate-cysteine ligase, catalytic subunit |
GCLM | glutamate-cysteine ligase, modifier subunit |
HIST1H2BG | histone cluster 1, H2bg |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HMOX1 | heme oxygenase 1 |
HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
LY86 | lymphocyte antigen 86 |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
NUCB2 | nucleobindin 2 |
OPN3 | opsin 3 |
PIR | pirin (iron-binding nuclear protein) |
PPAP2B | phosphatidic acid phosphatase type 2B |
PSAP | prosaposin |
RRBP1 | ribosome binding protein 1 |
S100A12 | S100 calcium binding protein A12 |
SELL | selectin L |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
TNC | tenascin C |
TXNRD1 | thioredoxin reductase 1 |
TYROBP | TYRO protein tyrosine kinase binding protein |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
UGDH | UDP-glucose 6-dehydrogenase |
ZNF91 | zinc finger protein 91 |
Symbol | Name |
---|---|
ADD3 | adducin 3 (gamma) |
CCND2 | cyclin D2 |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
COL3A1 | collagen, type III, alpha 1 |
CPE | carboxypeptidase E |
CRIP1 | cysteine-rich protein 1 (intestinal) |
CXADR | coxsackie virus and adenovirus receptor |
DLK1 | delta-like 1 homolog (Drosophila) |
DMD | dystrophin |
ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
EPCAM | epithelial cell adhesion molecule |
FABP1 | fatty acid binding protein 1, liver |
FAM198B | family with sequence similarity 198, member B |
GJA1 | gap junction protein, alpha 1, 43kDa |
GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
HEPH | hephaestin |
HOXB6 | homeobox B6 |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
IRS1 | insulin receptor substrate 1 |
ITM2A | integral membrane protein 2A |
LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
MAP7 | microtubule-associated protein 7 |
MB | myoglobin |
MECOM | MDS1 and EVI1 complex locus |
MEG3 | maternally expressed 3 (non-protein coding) |
MTA1 | metastasis associated 1 |
NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
ORM1 | orosomucoid 1 |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
PEG10 | paternally expressed 10 |
PEG3 | paternally expressed 3 |
PODXL | podocalyxin-like |
POSTN | periostin, osteoblast specific factor |
SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
SEPW1 | selenoprotein W, 1 |
SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
TSPAN8 | tetraspanin 8 |