Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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131 genes differentially expressed following the BRD-K15086322_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ALOX5 | arachidonate 5-lipoxygenase |
AMOTL2 | angiomotin like 2 |
ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
ARMCX2 | armadillo repeat containing, X-linked 2 |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
AXIN1 | axin 1 |
BGN | biglycan |
CCDC92 | coiled-coil domain containing 92 |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CDCA4 | cell division cycle associated 4 |
CKS2 | CDC28 protein kinase regulatory subunit 2 |
CLIC4 | chloride intracellular channel 4 |
CTSG | cathepsin G |
DDAH1 | dimethylarginine dimethylaminohydrolase 1 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DENND2D | DENN/MADD domain containing 2D |
DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
EPS8 | epidermal growth factor receptor pathway substrate 8 |
FOLR1 | folate receptor 1 (adult) |
FZD7 | frizzled class receptor 7 |
HOXB6 | homeobox B6 |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
IFI44L | interferon-induced protein 44-like |
IFITM1 | interferon induced transmembrane protein 1 |
ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
KAZN | kazrin, periplakin interacting protein |
KDM5D | lysine (K)-specific demethylase 5D |
LEPR | leptin receptor |
LGALS3 | lectin, galactoside-binding, soluble, 3 |
LST1 | leukocyte specific transcript 1 |
MAPT | microtubule-associated protein tau |
MET | MET proto-oncogene, receptor tyrosine kinase |
MFSD10 | major facilitator superfamily domain containing 10 |
MYB | v-myb avian myeloblastosis viral oncogene homolog |
NEFH | neurofilament, heavy polypeptide |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
OAT | ornithine aminotransferase |
PEG10 | paternally expressed 10 |
POLR1D | polymerase (RNA) I polypeptide D, 16kDa |
PTGES | prostaglandin E synthase |
PTX3 | pentraxin 3, long |
RGS2 | regulator of G-protein signaling 2 |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
SKAP2 | src kinase associated phosphoprotein 2 |
SLBP | stem-loop binding protein |
SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
SLIT2 | slit homolog 2 (Drosophila) |
SMAD6 | SMAD family member 6 |
TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
TGOLN2 | trans-golgi network protein 2 |
TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) |
UGCG | UDP-glucose ceramide glucosyltransferase |
ZBTB18 | zinc finger and BTB domain containing 18 |
ZNF586 | zinc finger protein 586 |
ZNF91 | zinc finger protein 91 |
Symbol | Name |
---|---|
ACKR3 | atypical chemokine receptor 3 |
ADA | adenosine deaminase |
ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
ARG2 | arginase 2 |
CADM1 | cell adhesion molecule 1 |
CALML3 | calmodulin-like 3 |
CD200 | CD200 molecule |
CD9 | CD9 molecule |
CLCA2 | chloride channel accessory 2 |
CLCA4 | chloride channel accessory 4 |
CLTB | clathrin, light chain B |
CLU | clusterin |
CPE | carboxypeptidase E |
CSRP1 | cysteine and glycine-rich protein 1 |
CSRP2 | cysteine and glycine-rich protein 2 |
CXADR | coxsackie virus and adenovirus receptor |
DSG2 | desmoglein 2 |
DUOX2 | dual oxidase 2 |
EGFL6 | EGF-like-domain, multiple 6 |
F11R | F11 receptor |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FBLN1 | fibulin 1 |
GAGE3 | G antigen 3 |
GLUL | glutamate-ammonia ligase |
GREM1 | gremlin 1, DAN family BMP antagonist |
GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
HAND2-AS1 | HAND2 antisense RNA 1 (head to head) |
IGHD | immunoglobulin heavy constant delta |
IGHM | immunoglobulin heavy constant mu |
IGL | immunoglobulin lambda locus |
IGSF3 | immunoglobulin superfamily, member 3 |
IL1RN | interleukin 1 receptor antagonist |
ITGA6 | integrin, alpha 6 |
ITM2C | integral membrane protein 2C |
JAM2 | junctional adhesion molecule 2 |
JCHAIN | joining chain of multimeric IgA and IgM |
KIAA0930 | KIAA0930 |
KRT13 | keratin 13, type I |
KRT5 | keratin 5, type II |
MAGEA3 | melanoma antigen family A3 |
MAGEA6 | melanoma antigen family A6 |
MAOA | monoamine oxidase A |
MAP7 | microtubule-associated protein 7 |
MEIS1 | Meis homeobox 1 |
MMP12 | matrix metallopeptidase 12 |
MMP3 | matrix metallopeptidase 3 |
MTUS1 | microtubule associated tumor suppressor 1 |
MYO1B | myosin IB |
NDN | necdin, melanoma antigen (MAGE) family member |
PALLD | palladin, cytoskeletal associated protein |
PER1 | period circadian clock 1 |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
PRAME | preferentially expressed antigen in melanoma |
RAD23B | RAD23 homolog B (S. cerevisiae) |
REG1A | regenerating islet-derived 1 alpha |
REG3A | regenerating islet-derived 3 alpha |
RFC5 | replication factor C (activator 1) 5, 36.5kDa |
ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
S100A7 | S100 calcium binding protein A7 |
S100A8 | S100 calcium binding protein A8 |
SCPEP1 | serine carboxypeptidase 1 |
SMC1A | structural maintenance of chromosomes 1A |
SPRR1A | small proline-rich protein 1A |
SPRR1B | small proline-rich protein 1B |
SPRR3 | small proline-rich protein 3 |
TBX3 | T-box 3 |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TMOD1 | tropomodulin 1 |
TP53I3 | tumor protein p53 inducible protein 3 |
XIST | X inactive specific transcript (non-protein coding) |
ZW10 | zw10 kinetochore protein |