BRD-K15588452_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K15588452_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CAB39 calcium binding protein 39
CD24 CD24 molecule
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM63A family with sequence similarity 63, member A
FBXL12 F-box and leucine-rich repeat protein 12
FDPS farnesyl diphosphate synthase
FOLR1 folate receptor 1 (adult)
GADD45B growth arrest and DNA-damage-inducible, beta
HIST1H2BG histone cluster 1, H2bg
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXC10 homeobox C10
HOXC6 homeobox C6
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSPA1A heat shock 70kDa protein 1A
IDI1 isopentenyl-diphosphate delta isomerase 1
INHBA inhibin, beta A
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LMCD1 LIM and cysteine-rich domains 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MGP matrix Gla protein
MSMO1 methylsterol monooxygenase 1
PSD3 pleckstrin and Sec7 domain containing 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFTPA2 surfactant protein A2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SOX9 SRY (sex determining region Y)-box 9
SPATS2L spermatogenesis associated, serine-rich 2-like
SPP1 secreted phosphoprotein 1
SQLE squalene epoxidase
SRC SRC proto-oncogene, non-receptor tyrosine kinase
THBS1 thrombospondin 1
TOX3 TOX high mobility group box family member 3
TUBA1A tubulin, alpha 1a
ZNF131 zinc finger protein 131

decreased expression

Symbol Name
BTG3 BTG family, member 3
CA2 carbonic anhydrase II
CDCA4 cell division cycle associated 4
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLCA4 chloride channel accessory 4
CP ceruloplasmin (ferroxidase)
DLD dihydrolipoamide dehydrogenase
DUSP6 dual specificity phosphatase 6
GJA1 gap junction protein, alpha 1, 43kDa
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI16 interferon, gamma-inducible protein 16
IGL immunoglobulin lambda locus
LOC100505650 uncharacterized LOC100505650
LTF lactotransferrin
PI3 peptidase inhibitor 3, skin-derived
PODXL podocalyxin-like
RND3 Rho family GTPase 3
S100A9 S100 calcium binding protein A9
SCGB2A1 secretoglobin, family 2A, member 1
SELENBP1 selenium binding protein 1
SLPI secretory leukocyte peptidase inhibitor
TFPI2 tissue factor pathway inhibitor 2
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