BRD-K15592317_CP466722_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K15592317_CP466722_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCL5 chemokine (C-C motif) ligand 5
CD8A CD8a molecule
CLEC2B C-type lectin domain family 2, member B
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
FCGBP Fc fragment of IgG binding protein
MUC5B mucin 5B, oligomeric mucus/gel-forming
MX2 MX dynamin-like GTPase 2
NELL2 NEL-like 2 (chicken)
NOTCH1 notch 1
PBX3 pre-B-cell leukemia homeobox 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRR5 proline rich 5 (renal)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SDC2 syndecan 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TFF3 trefoil factor 3 (intestinal)
VNN1 vanin 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA3 annexin A3
CA2 carbonic anhydrase II
CKB creatine kinase, brain
CTSH cathepsin H
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELANE elastase, neutrophil expressed
FOLR1 folate receptor 1 (adult)
KANK1 KN motif and ankyrin repeat domains 1
MPO myeloperoxidase
MRPS16 mitochondrial ribosomal protein S16
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
NT5E 5'-nucleotidase, ecto (CD73)
PRKD3 protein kinase D3
PTGDS prostaglandin D2 synthase 21kDa (brain)
QPCT glutaminyl-peptide cyclotransferase
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SUB1 SUB1 homolog (S. cerevisiae)
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
XIST X inactive specific transcript (non-protein coding)
Funding