Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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68 genes differentially expressed following the BRD-K15592317_CP466722_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
ADIRF | adipogenesis regulatory factor |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
BAALC | brain and acute leukemia, cytoplasmic |
CD40 | CD40 molecule, TNF receptor superfamily member 5 |
CD69 | CD69 molecule |
CHN1 | chimerin 1 |
CLU | clusterin |
CRIP1 | cysteine-rich protein 1 (intestinal) |
CTSK | cathepsin K |
CXCL5 | chemokine (C-X-C motif) ligand 5 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
EGR1 | early growth response 1 |
EGR3 | early growth response 3 |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
GPM6B | glycoprotein M6B |
MMP9 | matrix metallopeptidase 9 |
MSRA | methionine sulfoxide reductase A |
MTCL1 | microtubule crosslinking factor 1 |
NNMT | nicotinamide N-methyltransferase |
NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
PGC | progastricsin (pepsinogen C) |
PLBD1 | phospholipase B domain containing 1 |
S100P | S100 calcium binding protein P |
SGK1 | serum/glucocorticoid regulated kinase 1 |
SKAP2 | src kinase associated phosphoprotein 2 |
SPARCL1 | SPARC-like 1 (hevin) |
ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
STC2 | stanniocalcin 2 |
SYNE2 | spectrin repeat containing, nuclear envelope 2 |
TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
Symbol | Name |
---|---|
ACAT2 | acetyl-CoA acetyltransferase 2 |
ADCY1 | adenylate cyclase 1 (brain) |
AIM1 | absent in melanoma 1 |
ASPH | aspartate beta-hydroxylase |
BEX1 | brain expressed, X-linked 1 |
CCP110 | centriolar coiled coil protein 110kDa |
CDC25B | cell division cycle 25B |
COL5A2 | collagen, type V, alpha 2 |
CP | ceruloplasmin (ferroxidase) |
CRELD2 | cysteine-rich with EGF-like domains 2 |
DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
FXYD5 | FXYD domain containing ion transport regulator 5 |
GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
GNAS | GNAS complex locus |
GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
HMG20B | high mobility group 20B |
IFI44L | interferon-induced protein 44-like |
KRT18 | keratin 18, type I |
LAMB1 | laminin, beta 1 |
LRRC17 | leucine rich repeat containing 17 |
PDGFC | platelet derived growth factor C |
PXDN | peroxidasin |
RGS10 | regulator of G-protein signaling 10 |
RTN1 | reticulon 1 |
S100A7 | S100 calcium binding protein A7 |
S100A8 | S100 calcium binding protein A8 |
S100A9 | S100 calcium binding protein A9 |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SRGN | serglycin |
TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
TFPI2 | tissue factor pathway inhibitor 2 |
VAV3 | vav 3 guanine nucleotide exchange factor |