| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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123 genes differentially expressed following the BRD-K15600710_S1057_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ALDOC | aldolase C, fructose-bisphosphate |
| AMDHD2 | amidohydrolase domain containing 2 |
| AREG | amphiregulin |
| ASS1 | argininosuccinate synthase 1 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CADM1 | cell adhesion molecule 1 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| COLEC12 | collectin sub-family member 12 |
| CST3 | cystatin C |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| EGFL6 | EGF-like-domain, multiple 6 |
| EPAS1 | endothelial PAS domain protein 1 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FRY | furry homolog (Drosophila) |
| GAS6 | growth arrest-specific 6 |
| GSN | gelsolin |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HK2 | hexokinase 2 |
| HLA-E | major histocompatibility complex, class I, E |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI44L | interferon-induced protein 44-like |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IGL | immunoglobulin lambda locus |
| LCN2 | lipocalin 2 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| MSLN | mesothelin |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OPTN | optineurin |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGCC | regulator of cell cycle |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SFTPB | surfactant protein B |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SRPX | sushi-repeat containing protein, X-linked |
| STC1 | stanniocalcin 1 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| VAT1 | vesicle amine transport 1 |
| VNN1 | vanin 1 |
| Symbol | Name |
|---|---|
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit |
| BAG2 | BCL2-associated athanogene 2 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CCNA2 | cyclin A2 |
| CDC20 | cell division cycle 20 |
| CDCA8 | cell division cycle associated 8 |
| CLU | clusterin |
| COPS7A | COP9 signalosome subunit 7A |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EBNA1BP2 | EBNA1 binding protein 2 |
| ECT2 | epithelial cell transforming 2 |
| EIF5 | eukaryotic translation initiation factor 5 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FBXO3 | F-box protein 3 |
| FEN1 | flap structure-specific endonuclease 1 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GTF2A2 | general transcription factor IIA, 2, 12kDa |
| HAT1 | histone acetyltransferase 1 |
| HES1 | hes family bHLH transcription factor 1 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) |
| KIAA0101 | KIAA0101 |
| KIF20A | kinesin family member 20A |
| KIF2C | kinesin family member 2C |
| KRT7 | keratin 7, type II |
| LBH | limb bud and heart development |
| LIG1 | ligase I, DNA, ATP-dependent |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MELK | maternal embryonic leucine zipper kinase |
| MYCBP | MYC binding protein |
| NEK2 | NIMA-related kinase 2 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| PALLD | palladin, cytoskeletal associated protein |
| PCNA | proliferating cell nuclear antigen |
| PLK2 | polo-like kinase 2 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| POP4 | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) |
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRPF4 | pre-mRNA processing factor 4 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 |
| PSPH | phosphoserine phosphatase |
| PXMP2 | peroxisomal membrane protein 2, 22kDa |
| RBP1 | retinol binding protein 1, cellular |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RND3 | Rho family GTPase 3 |
| RPA3 | replication protein A3, 14kDa |
| RRM2 | ribonucleotide reductase M2 |
| SEPW1 | selenoprotein W, 1 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) |
| SNRPG | small nuclear ribonucleoprotein polypeptide G |
| STMN1 | stathmin 1 |
| TMEM176B | transmembrane protein 176B |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TOX3 | TOX high mobility group box family member 3 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 |
| TSPAN12 | tetraspanin 12 |
| TXNDC9 | thioredoxin domain containing 9 |
| WDR61 | WD repeat domain 61 |
| WWTR1 | WW domain containing transcription regulator 1 |
| ZNF586 | zinc finger protein 586 |
