Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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112 genes differentially expressed following the BRD-K15791587_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACAT2 | acetyl-CoA acetyltransferase 2 |
ACSL3 | acyl-CoA synthetase long-chain family member 3 |
AK4 | adenylate kinase 4 |
BASP1 | brain abundant, membrane attached signal protein 1 |
CCNG2 | cyclin G2 |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
CHMP4A | charged multivesicular body protein 4A |
CRIP1 | cysteine-rich protein 1 (intestinal) |
DDIT4 | DNA-damage-inducible transcript 4 |
DHCR24 | 24-dehydrocholesterol reductase |
DHCR7 | 7-dehydrocholesterol reductase |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
EXT1 | exostosin glycosyltransferase 1 |
FASN | fatty acid synthase |
FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
FGG | fibrinogen gamma chain |
GLUL | glutamate-ammonia ligase |
HBB | hemoglobin, beta |
HILPDA | hypoxia inducible lipid droplet-associated |
HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
ITM2C | integral membrane protein 2C |
JUP | junction plakoglobin |
LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
LIMCH1 | LIM and calponin homology domains 1 |
LPCAT1 | lysophosphatidylcholine acyltransferase 1 |
MAGED2 | melanoma antigen family D2 |
MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MN1 | meningioma (disrupted in balanced translocation) 1 |
MSMO1 | methylsterol monooxygenase 1 |
NARFL | nuclear prelamin A recognition factor-like |
NPY1R | neuropeptide Y receptor Y1 |
NRIP3 | nuclear receptor interacting protein 3 |
OLFML3 | olfactomedin-like 3 |
PAIP1 | poly(A) binding protein interacting protein 1 |
PCDH17 | protocadherin 17 |
PENK | proenkephalin |
PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
PNMA2 | paraneoplastic Ma antigen 2 |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
RALGDS | ral guanine nucleotide dissociation stimulator |
REEP1 | receptor accessory protein 1 |
S100A8 | S100 calcium binding protein A8 |
SC5D | sterol-C5-desaturase |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SPARCL1 | SPARC-like 1 (hevin) |
SQLE | squalene epoxidase |
TMEM100 | transmembrane protein 100 |
TUBA1A | tubulin, alpha 1a |
TXNIP | thioredoxin interacting protein |
TYROBP | TYRO protein tyrosine kinase binding protein |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
ZDHHC11 | zinc finger, DHHC-type containing 11 |
ZNF586 | zinc finger protein 586 |
ZSCAN18 | zinc finger and SCAN domain containing 18 |
Symbol | Name |
---|---|
ACTN1 | actinin, alpha 1 |
AKAP12 | A kinase (PRKA) anchor protein 12 |
ANXA3 | annexin A3 |
BACE2 | beta-site APP-cleaving enzyme 2 |
CALD1 | caldesmon 1 |
CCT2 | chaperonin containing TCP1, subunit 2 (beta) |
CD27 | CD27 molecule |
COTL1 | coactosin-like F-actin binding protein 1 |
CTGF | connective tissue growth factor |
CTPS1 | CTP synthase 1 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
DUSP6 | dual specificity phosphatase 6 |
EIF5 | eukaryotic translation initiation factor 5 |
ELL2 | elongation factor, RNA polymerase II, 2 |
EREG | epiregulin |
ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
FAM198B | family with sequence similarity 198, member B |
FERMT2 | fermitin family member 2 |
FOLR1 | folate receptor 1 (adult) |
FOSL1 | FOS-like antigen 1 |
HBEGF | heparin-binding EGF-like growth factor |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
IER3 | immediate early response 3 |
IFI16 | interferon, gamma-inducible protein 16 |
IFRD2 | interferon-related developmental regulator 2 |
IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
LAPTM4B | lysosomal protein transmembrane 4 beta |
LEF1 | lymphoid enhancer-binding factor 1 |
LTF | lactotransferrin |
MBNL2 | muscleblind-like splicing regulator 2 |
NOP16 | NOP16 nucleolar protein |
PDLIM5 | PDZ and LIM domain 5 |
PPIF | peptidylprolyl isomerase F |
RCAN1 | regulator of calcineurin 1 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SDC2 | syndecan 2 |
SERBP1 | SERPINE1 mRNA binding protein 1 |
SOX4 | SRY (sex determining region Y)-box 4 |
SOX9 | SRY (sex determining region Y)-box 9 |
STK17A | serine/threonine kinase 17a |
SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TFF1 | trefoil factor 1 |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TJP2 | tight junction protein 2 |
TLR4 | toll-like receptor 4 |
TPM1 | tropomyosin 1 (alpha) |
TRAC | T cell receptor alpha constant |
TUBB2A | tubulin, beta 2A class IIa |
WDR1 | WD repeat domain 1 |