BRD-K15834839_-666_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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55 genes differentially expressed following the BRD-K15834839_-666_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BIK BCL2-interacting killer (apoptosis-inducing)
CADM1 cell adhesion molecule 1
CD24 CD24 molecule
COL4A5 collagen, type IV, alpha 5
EGR1 early growth response 1
EPCAM epithelial cell adhesion molecule
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
HHEX hematopoietically expressed homeobox
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KRT19 keratin 19, type I
LOC100505650 uncharacterized LOC100505650
MMP12 matrix metallopeptidase 12
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MUC1 mucin 1, cell surface associated
NFE2L2 nuclear factor, erythroid 2-like 2
PLAU plasminogen activator, urokinase
PPL periplakin
PRAME preferentially expressed antigen in melanoma
PRSS21 protease, serine, 21 (testisin)
RAB25 RAB25, member RAS oncogene family
SFRP4 secreted frizzled-related protein 4
SOX2 SRY (sex determining region Y)-box 2
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STAR steroidogenic acute regulatory protein
TACSTD2 tumor-associated calcium signal transducer 2
TGFA transforming growth factor, alpha

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
APOD apolipoprotein D
BGN biglycan
CA12 carbonic anhydrase XII
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCL12 chemokine (C-X-C motif) ligand 12
DLD dihydrolipoamide dehydrogenase
EIF4B eukaryotic translation initiation factor 4B
FAM57A family with sequence similarity 57, member A
FSTL1 follistatin-like 1
G0S2 G0/G1 switch 2
GOLT1B golgi transport 1B
GPC4 glypican 4
GPX1 glutathione peroxidase 1
GREM1 gremlin 1, DAN family BMP antagonist
LYPLA1 lysophospholipase I
MAGED1 melanoma antigen family D1
PIP prolactin-induced protein
PRDX2 peroxiredoxin 2
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RBM3 RNA binding motif (RNP1, RRM) protein 3
TMEM45A transmembrane protein 45A
TMEM47 transmembrane protein 47
TMEM50A transmembrane protein 50A
TNS1 tensin 1
TSC22D3 TSC22 domain family, member 3
VCAN versican