BRD-K16290432_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

20 genes differentially expressed following the BRD-K16290432_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CTGF connective tissue growth factor
DDIT4 DNA-damage-inducible transcript 4
HMOX1 heme oxygenase 1
LXN latexin
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPDC1 neural proliferation, differentiation and control, 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSC22D3 TSC22 domain family, member 3
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
CD44 CD44 molecule (Indian blood group)
DEGS1 delta(4)-desaturase, sphingolipid 1
LPAR6 lysophosphatidic acid receptor 6
PMM2 phosphomannomutase 2
RNF167 ring finger protein 167
SMAD1 SMAD family member 1
STC1 stanniocalcin 1
Funding