BRD-K16472144_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K16472144_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ARL4C ADP-ribosylation factor-like 4C
AUTS2 autism susceptibility candidate 2
BEX4 brain expressed, X-linked 4
BIK BCL2-interacting killer (apoptosis-inducing)
BLNK B-cell linker
CD40 CD40 molecule, TNF receptor superfamily member 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLEC11A C-type lectin domain family 11, member A
COL1A2 collagen, type I, alpha 2
CP ceruloplasmin (ferroxidase)
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
DENND1B DENN/MADD domain containing 1B
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DOK5 docking protein 5
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF13 fibroblast growth factor 13
FOS FBJ murine osteosarcoma viral oncogene homolog
FTH1 ferritin, heavy polypeptide 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
H2AFV H2A histone family, member V
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGFBP7 insulin-like growth factor binding protein 7
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
KRT18 keratin 18, type I
LDB2 LIM domain binding 2
LMO3 LIM domain only 3 (rhombotin-like 2)
LYN LYN proto-oncogene, Src family tyrosine kinase
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDE2A phosphodiesterase 2A, cGMP-stimulated
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POU2AF1 POU class 2 associating factor 1
PPOX protoporphyrinogen oxidase
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RFTN1 raftlin, lipid raft linker 1
RGS1 regulator of G-protein signaling 1
RND3 Rho family GTPase 3
SCG5 secretogranin V
SHB Src homology 2 domain containing adaptor protein B
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
STS steroid sulfatase (microsomal), isozyme S
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TM9SF3 transmembrane 9 superfamily member 3
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
TSPAN12 tetraspanin 12
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VAMP8 vesicle-associated membrane protein 8

decreased expression

Symbol Name
AFP alpha-fetoprotein
APOA2 apolipoprotein A-II
CDCA4 cell division cycle associated 4
CST3 cystatin C
CXCL5 chemokine (C-X-C motif) ligand 5
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GAS1 growth arrest-specific 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI44L interferon-induced protein 44-like
IFRD2 interferon-related developmental regulator 2
KIAA0125 KIAA0125
LOX lysyl oxidase
MSX1 msh homeobox 1
NPY neuropeptide Y
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRR7 proline rich 7 (synaptic)
RGS2 regulator of G-protein signaling 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TMED3 transmembrane emp24 protein transport domain containing 3
TMPRSS2 transmembrane protease, serine 2