BRD-K16478699_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K16478699_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACKR3 atypical chemokine receptor 3
ADIRF adipogenesis regulatory factor
APOD apolipoprotein D
ARMCX2 armadillo repeat containing, X-linked 2
ASS1 argininosuccinate synthase 1
AUTS2 autism susceptibility candidate 2
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
COL11A1 collagen, type XI, alpha 1
COMP cartilage oligomeric matrix protein
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
CRYAB crystallin, alpha B
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ESRP1 epithelial splicing regulatory protein 1
FHL1 four and a half LIM domains 1
FRY furry homolog (Drosophila)
GSE1 Gse1 coiled-coil protein
GSTM3 glutathione S-transferase mu 3 (brain)
HIST1H1C histone cluster 1, H1c
HOPX HOP homeobox
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
METTL7A methyltransferase like 7A
MGP matrix Gla protein
MN1 meningioma (disrupted in balanced translocation) 1
MYO1D myosin ID
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
SESN1 sestrin 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC38A1 solute carrier family 38, member 1
SOX2 SRY (sex determining region Y)-box 2
TFF3 trefoil factor 3 (intestinal)
TRIB3 tribbles pseudokinase 3

decreased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BAD BCL2-associated agonist of cell death
BASP1 brain abundant, membrane attached signal protein 1
CANT1 calcium activated nucleotidase 1
CCND1 cyclin D1
CD44 CD44 molecule (Indian blood group)
CXCL5 chemokine (C-X-C motif) ligand 5
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
ETV5 ets variant 5
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FASTKD5 FAST kinase domains 5
FOSL1 FOS-like antigen 1
HBD hemoglobin, delta
HBEGF heparin-binding EGF-like growth factor
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IRS2 insulin receptor substrate 2
ITGA6 integrin, alpha 6
LAMC2 laminin, gamma 2
LCN2 lipocalin 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NOP16 NOP16 nucleolar protein
PCDH9 protocadherin 9
PLAT plasminogen activator, tissue
SIK1 salt-inducible kinase 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SOX9 SRY (sex determining region Y)-box 9
SPRY2 sprouty homolog 2 (Drosophila)
STK17A serine/threonine kinase 17a
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESC tescalcin
TGFA transforming growth factor, alpha
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TRAPPC3 trafficking protein particle complex 3
XK X-linked Kx blood group
ZW10 zw10 kinetochore protein