BRD-K16478699_PLX-4720_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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60 genes differentially expressed following the BRD-K16478699_PLX-4720_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA1 annexin A1
AZU1 azurocidin 1
C6ORF62 chromosome 6 open reading frame 62
CDK19 cyclin-dependent kinase 19
CFD complement factor D (adipsin)
CLU clusterin
CSTA cystatin A (stefin A)
DSP desmoplakin
ELANE elastase, neutrophil expressed
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB4 erb-b2 receptor tyrosine kinase 4
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HNMT histamine N-methyltransferase
IFI44L interferon-induced protein 44-like
IGFBP7 insulin-like growth factor binding protein 7
JAG1 jagged 1
LAPTM4B lysosomal protein transmembrane 4 beta
LTF lactotransferrin
MARCKS myristoylated alanine-rich protein kinase C substrate
MSX1 msh homeobox 1
MUC1 mucin 1, cell surface associated
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PDLIM5 PDZ and LIM domain 5
PRTN3 proteinase 3
PSPH phosphoserine phosphatase
RPS11 ribosomal protein S11
SH3YL1 SH3 and SYLF domain containing 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SORBS2 sorbin and SH3 domain containing 2
SOX9 SRY (sex determining region Y)-box 9

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ATF3 activating transcription factor 3
CD9 CD9 molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
CSRP2 cysteine and glycine-rich protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DST dystonin
GATA3 GATA binding protein 3
GDF15 growth differentiation factor 15
GUCY1B3 guanylate cyclase 1, soluble, beta 3
LITAF lipopolysaccharide-induced TNF factor
LRP4 low density lipoprotein receptor-related protein 4
MMP12 matrix metallopeptidase 12
NPY1R neuropeptide Y receptor Y1
NTS neurotensin
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLEKHA5 pleckstrin homology domain containing, family A member 5
PSD3 pleckstrin and Sec7 domain containing 3
SLC38A1 solute carrier family 38, member 1
SPRY2 sprouty homolog 2 (Drosophila)
SYNGR3 synaptogyrin 3
TCF21 transcription factor 21
TFF3 trefoil factor 3 (intestinal)
TNC tenascin C
TPBG trophoblast glycoprotein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
URI1 URI1, prefoldin-like chaperone