Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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72 genes differentially expressed following the BRD-K16947188_N-(2-ethoxyphenyl)-4-morpholino-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-amine hw-gc-act07_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ALB | albumin |
CASP1 | caspase 1, apoptosis-related cysteine peptidase |
CCNA1 | cyclin A1 |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
EPAS1 | endothelial PAS domain protein 1 |
EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
FBN2 | fibrillin 2 |
FLNA | filamin A, alpha |
FRZB | frizzled-related protein |
GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
HNMT | histamine N-methyltransferase |
HOMER3 | homer scaffolding protein 3 |
IFI27 | interferon, alpha-inducible protein 27 |
ITGB4 | integrin, beta 4 |
LGALS3 | lectin, galactoside-binding, soluble, 3 |
NDRG1 | N-myc downstream regulated 1 |
PCP4 | Purkinje cell protein 4 |
PEG10 | paternally expressed 10 |
PFKL | phosphofructokinase, liver |
PLAGL1 | pleiomorphic adenoma gene-like 1 |
PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
PTN | pleiotrophin |
RHOBTB1 | Rho-related BTB domain containing 1 |
RNF167 | ring finger protein 167 |
S100P | S100 calcium binding protein P |
SDC1 | syndecan 1 |
SERINC3 | serine incorporator 3 |
SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
SOX4 | SRY (sex determining region Y)-box 4 |
ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
STK26 | serine/threonine protein kinase 26 |
TGFBI | transforming growth factor, beta-induced, 68kDa |
TNS3 | tensin 3 |
TXNIP | thioredoxin interacting protein |
UPP1 | uridine phosphorylase 1 |
ZFP36L2 | ZFP36 ring finger protein-like 2 |
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AGTR1 | angiotensin II receptor, type 1 |
ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
C8ORF4 | chromosome 8 open reading frame 4 |
CNN3 | calponin 3, acidic |
CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
DEGS1 | delta(4)-desaturase, sphingolipid 1 |
GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
GAS1 | growth arrest-specific 1 |
GPATCH8 | G patch domain containing 8 |
HNRNPL | heterogeneous nuclear ribonucleoprotein L |
HOXB2 | homeobox B2 |
IGHD | immunoglobulin heavy constant delta |
IGHM | immunoglobulin heavy constant mu |
KIAA0101 | KIAA0101 |
KIAA0485 | uncharacterized LOC57235 |
LIMA1 | LIM domain and actin binding 1 |
MUC4 | mucin 4, cell surface associated |
MYH10 | myosin, heavy chain 10, non-muscle |
NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
PIP | prolactin-induced protein |
PRKCH | protein kinase C, eta |
RGS1 | regulator of G-protein signaling 1 |
RGS10 | regulator of G-protein signaling 10 |
SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
TCF4 | transcription factor 4 |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TMEM230 | transmembrane protein 230 |
TYMS | thymidylate synthetase |