| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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162 genes differentially expressed following the BRD-K17743125_belinostat_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADD3 | adducin 3 (gamma) |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) |
| ALDOC | aldolase C, fructose-bisphosphate |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANOS1 | anosmin 1 |
| ARHGAP29 | Rho GTPase activating protein 29 |
| BAD | BCL2-associated agonist of cell death |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCNG2 | cyclin G2 |
| CD14 | CD14 molecule |
| CD24 | CD24 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CRISP3 | cysteine-rich secretory protein 3 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| DAPK1 | death-associated protein kinase 1 |
| DBN1 | drebrin 1 |
| DMXL2 | Dmx-like 2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FAM117A | family with sequence similarity 117, member A |
| FCGBP | Fc fragment of IgG binding protein |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FOXO4 | forkhead box O4 |
| FUCA1 | fucosidase, alpha-L- 1, tissue |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GRN | granulin |
| H1F0 | H1 histone family, member 0 |
| HOOK2 | hook microtubule-tethering protein 2 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| HSPB1 | heat shock 27kDa protein 1 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble |
| IDS | iduronate 2-sulfatase |
| IFT57 | intraflagellar transport 57 |
| LRRC16A | leucine rich repeat containing 16A |
| LTA4H | leukotriene A4 hydrolase |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MEGF9 | multiple EGF-like-domains 9 |
| METRN | meteorin, glial cell differentiation regulator |
| MFAP5 | microfibrillar associated protein 5 |
| MID1 | midline 1 |
| MME | membrane metallo-endopeptidase |
| MSX1 | msh homeobox 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| NAV2 | neuron navigator 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPC2 | Niemann-Pick disease, type C2 |
| PLA2G15 | phospholipase A2, group XV |
| POLR2E | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa |
| PRSS23 | protease, serine, 23 |
| REG1A | regenerating islet-derived 1 alpha |
| RTN3 | reticulon 3 |
| SDC2 | syndecan 2 |
| SEPHS2 | selenophosphate synthetase 2 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SNN | stannin |
| SNX2 | sorting nexin 2 |
| SQSTM1 | sequestosome 1 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 |
| THY1 | Thy-1 cell surface antigen |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNS3 | tensin 3 |
| TPP1 | tripeptidyl peptidase I |
| TRIM2 | tripartite motif containing 2 |
| TSPAN4 | tetraspanin 4 |
| TUBA1A | tubulin, alpha 1a |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB2B | tubulin, beta 2B class IIb |
| VAT1 | vesicle amine transport 1 |
| WDR7 | WD repeat domain 7 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WWOX | WW domain containing oxidoreductase |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
| ACAT1 | acetyl-CoA acetyltransferase 1 |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| AREG | amphiregulin |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| C1QBP | complement component 1, q subcomponent binding protein |
| C7 | complement component 7 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CD38 | CD38 molecule |
| CD48 | CD48 molecule |
| CD58 | CD58 molecule |
| CD69 | CD69 molecule |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYTIP | cytohesin 1 interacting protein |
| DCTD | dCMP deaminase |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FERMT1 | fermitin family member 1 |
| FGG | fibrinogen gamma chain |
| FHL2 | four and a half LIM domains 2 |
| FZD10 | frizzled class receptor 10 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GUSBP11 | glucuronidase, beta pseudogene 11 |
| HBB | hemoglobin, beta |
| HN1L | hematological and neurological expressed 1-like |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| IGF1 | insulin-like growth factor 1 (somatomedin C) |
| IGHM | immunoglobulin heavy constant mu |
| IGL | immunoglobulin lambda locus |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| INPP1 | inositol polyphosphate-1-phosphatase |
| IPO13 | importin 13 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 |
| ITGB5 | integrin, beta 5 |
| JADE2 | jade family PHD finger 2 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KIAA0101 | KIAA0101 |
| KLK10 | kallikrein-related peptidase 10 |
| KLK11 | kallikrein-related peptidase 11 |
| KLK6 | kallikrein-related peptidase 6 |
| KRT13 | keratin 13, type I |
| LYPLA1 | lysophospholipase I |
| MANSC1 | MANSC domain containing 1 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
| MAPK13 | mitogen-activated protein kinase 13 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) |
| MSLN | mesothelin |
| MSMB | microseminoprotein, beta- |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| NCAPD3 | non-SMC condensin II complex, subunit D3 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDLIM1 | PDZ and LIM domain 1 |
| RPIA | ribose 5-phosphate isomerase A |
| RRM2 | ribonucleotide reductase M2 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SLC35F2 | solute carrier family 35, member F2 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SQLE | squalene epoxidase |
| SRGN | serglycin |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| TFB2M | transcription factor B2, mitochondrial |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TP53 | tumor protein p53 |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TSPAN8 | tetraspanin 8 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| XBP1 | X-box binding protein 1 |
| XIST | X inactive specific transcript (non-protein coding) |
