| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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72 genes differentially expressed following the BRD-K17743125_belinostat_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ARG1 | arginase 1 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CORO1A | coronin, actin binding protein, 1A |
| CTSC | cathepsin C |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| EPHB2 | EPH receptor B2 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FBN2 | fibrillin 2 |
| FNBP1L | formin binding protein 1-like |
| FOXO4 | forkhead box O4 |
| G0S2 | G0/G1 switch 2 |
| HOPX | HOP homeobox |
| IFI27 | interferon, alpha-inducible protein 27 |
| IL32 | interleukin 32 |
| JAM2 | junctional adhesion molecule 2 |
| KLF2 | Kruppel-like factor 2 |
| LCN2 | lipocalin 2 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MFAP2 | microfibrillar-associated protein 2 |
| MVP | major vault protein |
| PLA2G16 | phospholipase A2, group XVI |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PRKCH | protein kinase C, eta |
| RHOB | ras homolog family member B |
| RUNX1 | runt-related transcription factor 1 |
| S100A12 | S100 calcium binding protein A12 |
| S100A9 | S100 calcium binding protein A9 |
| S100P | S100 calcium binding protein P |
| STC1 | stanniocalcin 1 |
| TCF4 | transcription factor 4 |
| THBS4 | thrombospondin 4 |
| TLE4 | transducin-like enhancer of split 4 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| VCAM1 | vascular cell adhesion molecule 1 |
| VDAC1 | voltage-dependent anion channel 1 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| CCNA2 | cyclin A2 |
| CPE | carboxypeptidase E |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CTSB | cathepsin B |
| CTSH | cathepsin H |
| CXADR | coxsackie virus and adenovirus receptor |
| DEK | DEK proto-oncogene |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DNM1L | dynamin 1-like |
| FOLR1 | folate receptor 1 (adult) |
| GDF15 | growth differentiation factor 15 |
| GTPBP8 | GTP-binding protein 8 (putative) |
| HOXB2 | homeobox B2 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
| KIF14 | kinesin family member 14 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| METTL7A | methyltransferase like 7A |
| MSMB | microseminoprotein, beta- |
| NPTXR | neuronal pentraxin receptor |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 |
| PEG10 | paternally expressed 10 |
| PRPF4 | pre-mRNA processing factor 4 |
| RAD51C | RAD51 paralog C |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TSC22D1 | TSC22 domain family, member 1 |
