BRD-K17743697_-666_HT29_6.0_h_10.0_um Gene Set
Genes
30 genes differentially expressed following the BRD-K17743697_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
CLU
|
clusterin
|
|
DHCR7
|
7-dehydrocholesterol reductase
|
|
EFNB2
|
ephrin-B2
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
|
INSIG1
|
insulin induced gene 1
|
|
LDLR
|
low density lipoprotein receptor
|
|
MSMO1
|
methylsterol monooxygenase 1
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
|
SQLE
|
squalene epoxidase
|
|
TRAPPC3
|
trafficking protein particle complex 3
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
decreased expression
| Symbol |
Name |
|
A2M
|
alpha-2-macroglobulin
|
|
AREG
|
amphiregulin
|
|
EDNRB
|
endothelin receptor type B
|
|
EGR1
|
early growth response 1
|
|
HBB
|
hemoglobin, beta
|
|
HEY1
|
hes-related family bHLH transcription factor with YRPW motif 1
|
|
KANK1
|
KN motif and ankyrin repeat domains 1
|
|
LXN
|
latexin
|
|
PPAP2B
|
phosphatidic acid phosphatase type 2B
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
|
RGCC
|
regulator of cell cycle
|
|
RGS2
|
regulator of G-protein signaling 2
|
|
RGS5
|
regulator of G-protein signaling 5
|
|
SNAI2
|
snail family zinc finger 2
|
|
TIMP3
|
TIMP metallopeptidase inhibitor 3
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
|
TUBB2B
|
tubulin, beta 2B class IIb
|
