BRD-K19220233_JNK-9L_A549_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

130 genes differentially expressed following the BRD-K19220233_JNK-9L_A549_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACP6 acid phosphatase 6, lysophosphatidic
C6ORF48 chromosome 6 open reading frame 48
CBR3 carbonyl reductase 3
CCDC85B coiled-coil domain containing 85B
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
COL6A2 collagen, type VI, alpha 2
COMP cartilage oligomeric matrix protein
DSP desmoplakin
ESRP1 epithelial splicing regulatory protein 1
FERMT1 fermitin family member 1
FOSL1 FOS-like antigen 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOPX HOP homeobox
HSPA1A heat shock 70kDa protein 1A
IGFBP7 insulin-like growth factor binding protein 7
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KCTD12 potassium channel tetramerization domain containing 12
KLF5 Kruppel-like factor 5 (intestinal)
LGALS4 lectin, galactoside-binding, soluble, 4
MECOM MDS1 and EVI1 complex locus
OXA1L oxidase (cytochrome c) assembly 1-like
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PNKP polynucleotide kinase 3'-phosphatase
PODXL podocalyxin-like
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PRR7 proline rich 7 (synaptic)
PTDSS1 phosphatidylserine synthase 1
RBM34 RNA binding motif protein 34
SDC4 syndecan 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
STK10 serine/threonine kinase 10
TIMP3 TIMP metallopeptidase inhibitor 3
TSPAN4 tetraspanin 4
TSTA3 tissue specific transplantation antigen P35B

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ADI1 acireductone dioxygenase 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
ANXA2 annexin A2
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOD apolipoprotein D
AQP3 aquaporin 3 (Gill blood group)
ATP9A ATPase, class II, type 9A
BAMBI BMP and activin membrane-bound inhibitor
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C4BPA complement component 4 binding protein, alpha
C6ORF62 chromosome 6 open reading frame 62
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDK19 cyclin-dependent kinase 19
CFLAR CASP8 and FADD-like apoptosis regulator
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLDN3 claudin 3
CLIC4 chloride intracellular channel 4
COL5A2 collagen, type V, alpha 2
CPM carboxypeptidase M
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DEFB1 defensin, beta 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL2 dihydropyrimidinase-like 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ETV1 ets variant 1
FOLR1 folate receptor 1 (adult)
GLRX glutaredoxin (thioltransferase)
H2AFV H2A histone family, member V
HBB hemoglobin, beta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HNMT histamine N-methyltransferase
HOXC6 homeobox C6
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP5 insulin-like growth factor binding protein 5
IL1R1 interleukin 1 receptor, type I
IRX5 iroquois homeobox 5
LGALS3 lectin, galactoside-binding, soluble, 3
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LXN latexin
MAGED1 melanoma antigen family D1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEGF9 multiple EGF-like-domains 9
MXI1 MAX interactor 1, dimerization protein
MYLK myosin light chain kinase
NR2F1 nuclear receptor subfamily 2, group F, member 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OLFML3 olfactomedin-like 3
PADI2 peptidyl arginine deiminase, type II
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PECR peroxisomal trans-2-enoyl-CoA reductase
PLBD1 phospholipase B domain containing 1
PON3 paraoxonase 3
PROS1 protein S (alpha)
PTN pleiotrophin
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RNASE4 ribonuclease, RNase A family, 4
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SGK1 serum/glucocorticoid regulated kinase 1
SKAP2 src kinase associated phosphoprotein 2
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLPI secretory leukocyte peptidase inhibitor
SNAP25 synaptosomal-associated protein, 25kDa
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STMN1 stathmin 1
SYT1 synaptotagmin I
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCF4 transcription factor 4
TMEM100 transmembrane protein 100
TMSB15A thymosin beta 15a
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
USP6NL USP6 N-terminal like
WNT5A wingless-type MMTV integration site family, member 5A
Funding