| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
242 genes differentially expressed following the BRD-K19220233_JNK-9L_BT20_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALB | albumin |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit |
| ANKRD36B | ankyrin repeat domain 36B |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit |
| AQP9 | aquaporin 9 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ASPN | asporin |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BCL2L1 | BCL2-like 1 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| BLNK | B-cell linker |
| C5AR1 | complement component 5a receptor 1 |
| CALB1 | calbindin 1, 28kDa |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CFB | complement factor B |
| CFI | complement factor I |
| COL11A1 | collagen, type XI, alpha 1 |
| CPD | carboxypeptidase D |
| CPE | carboxypeptidase E |
| CTGF | connective tissue growth factor |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DST | dystonin |
| DUSP2 | dual specificity phosphatase 2 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| ECM1 | extracellular matrix protein 1 |
| EGR1 | early growth response 1 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPCAM | epithelial cell adhesion molecule |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FGF13 | fibroblast growth factor 13 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOLR1 | folate receptor 1 (adult) |
| FPR1 | formyl peptide receptor 1 |
| FRY | furry homolog (Drosophila) |
| FST | follistatin |
| G0S2 | G0/G1 switch 2 |
| GAS6 | growth arrest-specific 6 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GLUL | glutamate-ammonia ligase |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 |
| GOLGA8B | golgin A8 family, member B |
| GPNMB | glycoprotein (transmembrane) nmb |
| GSAP | gamma-secretase activating protein |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| GUK1 | guanylate kinase 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HIST1H1C | histone cluster 1, H1c |
| HP | haptoglobin |
| HRSP12 | heat-responsive protein 12 |
| IDS | iduronate 2-sulfatase |
| IFI30 | interferon, gamma-inducible protein 30 |
| IFRD2 | interferon-related developmental regulator 2 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| MDFIC | MyoD family inhibitor domain containing |
| METTL5 | methyltransferase like 5 |
| MXRA5 | matrix-remodelling associated 5 |
| MXRA7 | matrix-remodelling associated 7 |
| MYO1B | myosin IB |
| NDFIP1 | Nedd4 family interacting protein 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PCBP2 | poly(rC) binding protein 2 |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLVAP | plasmalemma vesicle associated protein |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RBP4 | retinol binding protein 4, plasma |
| REEP5 | receptor accessory protein 5 |
| RRAGD | Ras-related GTP binding D |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SCARB2 | scavenger receptor class B, member 2 |
| SDC2 | syndecan 2 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SFRP1 | secreted frizzled-related protein 1 |
| SMYD3 | SET and MYND domain containing 3 |
| SRPR | signal recognition particle receptor (docking protein) |
| SSR4 | signal sequence receptor, delta |
| STC1 | stanniocalcin 1 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STK38L | serine/threonine kinase 38 like |
| STXBP6 | syntaxin binding protein 6 (amisyn) |
| TF | transferrin |
| TGFB1 | transforming growth factor, beta 1 |
| TGOLN2 | trans-golgi network protein 2 |
| THBS1 | thrombospondin 1 |
| THY1 | Thy-1 cell surface antigen |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 |
| TMEM259 | transmembrane protein 259 |
| TPP1 | tripeptidyl peptidase I |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSPAN7 | tetraspanin 7 |
| TUSC3 | tumor suppressor candidate 3 |
| TYROBP | TYRO protein tyrosine kinase binding protein |
| VEGFA | vascular endothelial growth factor A |
| Symbol | Name |
|---|---|
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATMIN | ATM interactor |
| AURKA | aurora kinase A |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BLCAP | bladder cancer associated protein |
| CAB39 | calcium binding protein 39 |
| CBR3 | carbonyl reductase 3 |
| CCNA2 | cyclin A2 |
| CCNB2 | cyclin B2 |
| CCNF | cyclin F |
| CDC20 | cell division cycle 20 |
| CDC25B | cell division cycle 25B |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDK19 | cyclin-dependent kinase 19 |
| CENPA | centromere protein A |
| CENPF | centromere protein F, 350/400kDa |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CLTA | clathrin, light chain A |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| EIF6 | eukaryotic translation initiation factor 6 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| FA2H | fatty acid 2-hydroxylase |
| FBXO21 | F-box protein 21 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FOXO3 | forkhead box O3 |
| FZD7 | frizzled class receptor 7 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GAL | galanin/GMAP prepropeptide |
| GATA3 | GATA binding protein 3 |
| GLOD4 | glyoxalase domain containing 4 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GPSM2 | G-protein signaling modulator 2 |
| GPX2 | glutathione peroxidase 2 |
| H2AFX | H2A histone family, member X |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXC6 | homeobox C6 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IST1 | increased sodium tolerance 1 homolog (yeast) |
| KAZN | kazrin, periplakin interacting protein |
| KIF20A | kinesin family member 20A |
| KLK6 | kallikrein-related peptidase 6 |
| KRT14 | keratin 14, type I |
| KRT15 | keratin 15, type I |
| KRT17 | keratin 17, type I |
| KRT23 | keratin 23, type I |
| KRT7 | keratin 7, type II |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LBR | lamin B receptor |
| LMNB1 | lamin B1 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MALL | mal, T-cell differentiation protein-like |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MMP7 | matrix metallopeptidase 7 |
| MSMB | microseminoprotein, beta- |
| NEK2 | NIMA-related kinase 2 |
| NNMT | nicotinamide N-methyltransferase |
| NOP56 | NOP56 ribonucleoprotein |
| NOSIP | nitric oxide synthase interacting protein |
| NOTCH2 | notch 2 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NRIP1 | nuclear receptor interacting protein 1 |
| NSFL1C | NSFL1 (p97) cofactor (p47) |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 |
| NUP62 | nucleoporin 62kDa |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| OPN3 | opsin 3 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PCNA | proliferating cell nuclear antigen |
| PLK1 | polo-like kinase 1 |
| PNP | purine nucleoside phosphorylase |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PUM1 | pumilio RNA-binding family member 1 |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RAE1 | ribonucleic acid export 1 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RNF114 | ring finger protein 114 |
| RNPS1 | RNA binding protein S1, serine-rich domain |
| S100A6 | S100 calcium binding protein A6 |
| S100A7 | S100 calcium binding protein A7 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SETX | senataxin |
| SFN | stratifin |
| SLC38A2 | solute carrier family 38, member 2 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMC4 | structural maintenance of chromosomes 4 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B |
| SOX9 | SRY (sex determining region Y)-box 9 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TLE4 | transducin-like enhancer of split 4 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TOX3 | TOX high mobility group box family member 3 |
| TP53 | tumor protein p53 |
| TPD52L1 | tumor protein D52-like 1 |
| TPX2 | TPX2, microtubule-associated |
| TRAPPC3 | trafficking protein particle complex 3 |
| TUBB4B | tubulin, beta 4B class IVb |
| TXLNA | taxilin alpha |
| TXNRD1 | thioredoxin reductase 1 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| USP22 | ubiquitin specific peptidase 22 |
| VCP | valosin containing protein |
| WDR82 | WD repeat domain 82 |
