BRD-K19220233_JNK-9L_BT20_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K19220233_JNK-9L_BT20_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CD52 CD52 molecule
CLDN3 claudin 3
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
CPB1 carboxypeptidase B1 (tissue)
EREG epiregulin
FBN1 fibrillin 1
FOLR1 folate receptor 1 (adult)
IFT57 intraflagellar transport 57
ISG15 ISG15 ubiquitin-like modifier
LAMC1 laminin, gamma 1 (formerly LAMB2)
MAL mal, T-cell differentiation protein
MMP7 matrix metallopeptidase 7
MUC16 mucin 16, cell surface associated
MYOF myoferlin
PAM peptidylglycine alpha-amidating monooxygenase
PAX8 paired box 8
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
VCAN versican
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARID4B AT rich interactive domain 4B (RBP1-like)
BHLHE40 basic helix-loop-helix family, member e40
BTG1 B-cell translocation gene 1, anti-proliferative
CCND2 cyclin D2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FAM117A family with sequence similarity 117, member A
FXYD3 FXYD domain containing ion transport regulator 3
FZD7 frizzled class receptor 7
GATA2 GATA binding protein 2
HMGB2 high mobility group box 2
IER5 immediate early response 5
JCHAIN joining chain of multimeric IgA and IgM
KDM5B lysine (K)-specific demethylase 5B
KRT15 keratin 15, type I
LMO2 LIM domain only 2 (rhombotin-like 1)
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCK1 NCK adaptor protein 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFIL3 nuclear factor, interleukin 3 regulated
NRIP1 nuclear receptor interacting protein 1
PLK2 polo-like kinase 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RNF19B ring finger protein 19B
RNPS1 RNA binding protein S1, serine-rich domain
S100P S100 calcium binding protein P
SEPP1 selenoprotein P, plasma, 1
SOX9 SRY (sex determining region Y)-box 9
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TXNL4B thioredoxin-like 4B
Funding