BRD-K19220233_JNK-9L_HME1_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K19220233_JNK-9L_HME1_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOD apolipoprotein D
CLIC3 chloride intracellular channel 3
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
EGR1 early growth response 1
EIF5A eukaryotic translation initiation factor 5A
ENOSF1 enolase superfamily member 1
GAA glucosidase, alpha; acid
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GDF15 growth differentiation factor 15
GMDS GDP-mannose 4,6-dehydratase
HBB hemoglobin, beta
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IL1B interleukin 1, beta
ITM2A integral membrane protein 2A
LTBP3 latent transforming growth factor beta binding protein 3
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MME membrane metallo-endopeptidase
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NMU neuromedin U
PSPH phosphoserine phosphatase
RNF130 ring finger protein 130
SATB1 SATB homeobox 1
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SNX10 sorting nexin 10
SORD sorbitol dehydrogenase
SYNE2 spectrin repeat containing, nuclear envelope 2
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
THBS2 thrombospondin 2
TPD52 tumor protein D52
TUSC3 tumor suppressor candidate 3
WDR61 WD repeat domain 61
ZCCHC24 zinc finger, CCHC domain containing 24
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AMIGO2 adhesion molecule with Ig-like domain 2
BAG5 BCL2-associated athanogene 5
BMP2 bone morphogenetic protein 2
C8ORF4 chromosome 8 open reading frame 4
CBR3 carbonyl reductase 3
CD9 CD9 molecule
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CKS2 CDC28 protein kinase regulatory subunit 2
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EIF5 eukaryotic translation initiation factor 5
FAM107A family with sequence similarity 107, member A
FASTKD5 FAST kinase domains 5
GADD45B growth arrest and DNA-damage-inducible, beta
GLIPR1 GLI pathogenesis-related 1
GPM6B glycoprotein M6B
GSPT2 G1 to S phase transition 2
HES1 hes family bHLH transcription factor 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
JAG1 jagged 1
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KLHL9 kelch-like family member 9
KRT5 keratin 5, type II
LIMCH1 LIM and calponin homology domains 1
LTF lactotransferrin
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP7 microtubule-associated protein 7
MAT2A methionine adenosyltransferase II, alpha
MED17 mediator complex subunit 17
MIR22HG MIR22 host gene
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIL3 nuclear factor, interleukin 3 regulated
NKX3-1 NK3 homeobox 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRIP1 nuclear receptor interacting protein 1
PDGFA platelet-derived growth factor alpha polypeptide
PLIN2 perilipin 2
PPAP2B phosphatidic acid phosphatase type 2B
PROM1 prominin 1
PTRH2 peptidyl-tRNA hydrolase 2
PTX3 pentraxin 3, long
RBM15 RNA binding motif protein 15
RGS2 regulator of G-protein signaling 2
RIN2 Ras and Rab interactor 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SOX4 SRY (sex determining region Y)-box 4
TACSTD2 tumor-associated calcium signal transducer 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
WEE1 WEE1 G2 checkpoint kinase
ZFP36L2 ZFP36 ring finger protein-like 2
Funding