BRD-K19220233_JNK-9L_MDAMB231_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K19220233_JNK-9L_MDAMB231_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRL2 adhesion G protein-coupled receptor L2
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
BHLHE40 basic helix-loop-helix family, member e40
CLDN10 claudin 10
CST6 cystatin E/M
CTSH cathepsin H
CXCL14 chemokine (C-X-C motif) ligand 14
DHRS3 dehydrogenase/reductase (SDR family) member 3
EGR1 early growth response 1
EIF3I eukaryotic translation initiation factor 3, subunit I
GPM6A glycoprotein M6A
GULP1 GULP, engulfment adaptor PTB domain containing 1
HOPX HOP homeobox
HOXC6 homeobox C6
IDE insulin-degrading enzyme
IDS iduronate 2-sulfatase
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHM immunoglobulin heavy constant mu
KIAA0226L KIAA0226-like
KLK11 kallikrein-related peptidase 11
KLK8 kallikrein-related peptidase 8
LAPTM4B lysosomal protein transmembrane 4 beta
LAPTM5 lysosomal protein transmembrane 5
LIMCH1 LIM and calponin homology domains 1
LYN LYN proto-oncogene, Src family tyrosine kinase
NQO1 NAD(P)H dehydrogenase, quinone 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIR pirin (iron-binding nuclear protein)
PLAT plasminogen activator, tissue
RBP1 retinol binding protein 1, cellular
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
TCF4 transcription factor 4
TCL1A T-cell leukemia/lymphoma 1A
TOM1L1 target of myb1 (chicken)-like 1

decreased expression

Symbol Name
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AHR aryl hydrocarbon receptor
AKAP13 A kinase (PRKA) anchor protein 13
ARL4C ADP-ribosylation factor-like 4C
ASXL2 additional sex combs like transcriptional regulator 2
BAMBI BMP and activin membrane-bound inhibitor
BARD1 BRCA1 associated RING domain 1
BTG1 B-cell translocation gene 1, anti-proliferative
C21ORF91 chromosome 21 open reading frame 91
CADM1 cell adhesion molecule 1
CAST calpastatin
CCNE2 cyclin E2
CD24 CD24 molecule
CDC25A cell division cycle 25A
CDKN2AIP CDKN2A interacting protein
CHD1 chromodomain helicase DNA binding protein 1
CLU clusterin
CREB1 cAMP responsive element binding protein 1
CXCL11 chemokine (C-X-C motif) ligand 11
DICER1 dicer 1, ribonuclease type III
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPHA3 EPH receptor A3
FAS Fas cell surface death receptor
FOXO1 forkhead box O1
FST follistatin
FZD7 frizzled class receptor 7
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GBP1 guanylate binding protein 1, interferon-inducible
GOSR1 golgi SNAP receptor complex member 1
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HEXIM1 hexamethylene bis-acetamide inducible 1
HOXA1 homeobox A1
ING3 inhibitor of growth family, member 3
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
KDM3A lysine (K)-specific demethylase 3A
KLF5 Kruppel-like factor 5 (intestinal)
KLHL21 kelch-like family member 21
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MED21 mediator complex subunit 21
NEFM neurofilament, medium polypeptide
NET1 neuroepithelial cell transforming 1
NFIL3 nuclear factor, interleukin 3 regulated
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRIP1 nuclear receptor interacting protein 1
POLR1C polymerase (RNA) I polypeptide C, 30kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PXDN peroxidasin
RCAN1 regulator of calcineurin 1
RIN2 Ras and Rab interactor 2
RPP38 ribonuclease P/MRP 38kDa subunit
RYBP RING1 and YY1 binding protein
S100A10 S100 calcium binding protein A10
SELE selectin E
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SNAI2 snail family zinc finger 2
SRSF7 serine/arginine-rich splicing factor 7
TMEM176B transmembrane protein 176B
TNPO1 transportin 1
TOB2 transducer of ERBB2, 2
TRA2A transformer 2 alpha homolog (Drosophila)
UBE3C ubiquitin protein ligase E3C
ZNF292 zinc finger protein 292
Funding