BRD-K19352500_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

27 genes differentially expressed following the BRD-K19352500_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
FADS1 fatty acid desaturase 1
FN1 fibronectin 1
INSIG1 insulin induced gene 1
KRT6B keratin 6B, type II
LDLR low density lipoprotein receptor
MFAP5 microfibrillar associated protein 5
MKNK2 MAP kinase interacting serine/threonine kinase 2
MSMO1 methylsterol monooxygenase 1
MT1X metallothionein 1X
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
S100A2 S100 calcium binding protein A2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
TF transferrin
VCAN versican

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
BACE2 beta-site APP-cleaving enzyme 2
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
PRDX4 peroxiredoxin 4
TSPAN13 tetraspanin 13
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)