BRD-K20141153_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K20141153_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCR2 chemokine (C-C motif) receptor 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CXCL9 chemokine (C-X-C motif) ligand 9
HLA-DOB major histocompatibility complex, class II, DO beta
LPAR6 lysophosphatidic acid receptor 6
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RTN1 reticulon 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TRIM2 tripartite motif containing 2
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DLC1 DLC1 Rho GTPase activating protein
EIF5A eukaryotic translation initiation factor 5A
FAM46A family with sequence similarity 46, member A
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
LPL lipoprotein lipase
NUP62 nucleoporin 62kDa
PTX3 pentraxin 3, long
QDPR quinoid dihydropteridine reductase
RGS4 regulator of G-protein signaling 4
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPATS2L spermatogenesis associated, serine-rich 2-like