| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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109 genes differentially expressed following the BRD-K20285085_fostamatinib_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABLIM1 | actin binding LIM protein 1 |
| ACKR3 | atypical chemokine receptor 3 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ANGPTL2 | angiopoietin-like 2 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| AQP1 | aquaporin 1 (Colton blood group) |
| ASPN | asporin |
| ASS1 | argininosuccinate synthase 1 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C1RL | complement component 1, r subcomponent-like |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CADM1 | cell adhesion molecule 1 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD24 | CD24 molecule |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CSNK1D | casein kinase 1, delta |
| CTSK | cathepsin K |
| ECH1 | enoyl CoA hydratase 1, peroxisomal |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EFNA1 | ephrin-A1 |
| FBLN1 | fibulin 1 |
| FCGBP | Fc fragment of IgG binding protein |
| FGFR2 | fibroblast growth factor receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GPNMB | glycoprotein (transmembrane) nmb |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HIST1H1C | histone cluster 1, H1c |
| HLA-B | major histocompatibility complex, class I, B |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| MAOA | monoamine oxidase A |
| MATN2 | matrilin 2 |
| MFAP2 | microfibrillar-associated protein 2 |
| NEBL | nebulette |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OLFML2A | olfactomedin-like 2A |
| PALLD | palladin, cytoskeletal associated protein |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PEG10 | paternally expressed 10 |
| PRKX | protein kinase, X-linked |
| RTN2 | reticulon 2 |
| SFRP4 | secreted frizzled-related protein 4 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNN | stannin |
| SQRDL | sulfide quinone reductase-like (yeast) |
| STON1 | stonin 1 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TKT | transketolase |
| TPD52L1 | tumor protein D52-like 1 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
| ADM | adrenomedullin |
| AK4 | adenylate kinase 4 |
| BDNF | brain-derived neurotrophic factor |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| CCND1 | cyclin D1 |
| CD44 | CD44 molecule (Indian blood group) |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| COL9A3 | collagen, type IX, alpha 3 |
| DOCK10 | dedicator of cytokinesis 10 |
| DUSP10 | dual specificity phosphatase 10 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FKBP11 | FK506 binding protein 11, 19 kDa |
| FOSL1 | FOS-like antigen 1 |
| FOXD1 | forkhead box D1 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GOLT1B | golgi transport 1B |
| GRPEL1 | GrpE-like 1, mitochondrial (E. coli) |
| GSTO1 | glutathione S-transferase omega 1 |
| HMGA2 | high mobility group AT-hook 2 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| IER3 | immediate early response 3 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| INSIG1 | insulin induced gene 1 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 |
| LDLR | low density lipoprotein receptor |
| MINA | MYC induced nuclear antigen |
| MOK | MOK protein kinase |
| MSMO1 | methylsterol monooxygenase 1 |
| NAV3 | neuron navigator 3 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
| PDGFC | platelet derived growth factor C |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PLAT | plasminogen activator, tissue |
| SACS | sacsin molecular chaperone |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 |
| SPAG4 | sperm associated antigen 4 |
| SSR1 | signal sequence receptor, alpha |
| STC1 | stanniocalcin 1 |
| STK17A | serine/threonine kinase 17a |
| TFRC | transferrin receptor |
| TGM2 | transglutaminase 2 |
| THAP11 | THAP domain containing 11 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| VEGFC | vascular endothelial growth factor C |
