| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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83 genes differentially expressed following the BRD-K20285085_fostamatinib_HME1_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BST2 | bone marrow stromal cell antigen 2 |
| CBR3 | carbonyl reductase 3 |
| CCNG2 | cyclin G2 |
| CEP57 | centrosomal protein 57kDa |
| CFI | complement factor I |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CPE | carboxypeptidase E |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP22 | dual specificity phosphatase 22 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR1 | early growth response 1 |
| ETV1 | ets variant 1 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) |
| FRZB | frizzled-related protein |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GPX3 | glutathione peroxidase 3 |
| H2AFV | H2A histone family, member V |
| HES1 | hes family bHLH transcription factor 1 |
| HMGB2 | high mobility group box 2 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IGL | immunoglobulin lambda locus |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KRT15 | keratin 15, type I |
| KRT17 | keratin 17, type I |
| LPL | lipoprotein lipase |
| MAOB | monoamine oxidase B |
| METTL7A | methyltransferase like 7A |
| MGP | matrix Gla protein |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NFIB | nuclear factor I/B |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| POSTN | periostin, osteoblast specific factor |
| POU2AF1 | POU class 2 associating factor 1 |
| PTN | pleiotrophin |
| PTPRC | protein tyrosine phosphatase, receptor type, C |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RGS2 | regulator of G-protein signaling 2 |
| SCG5 | secretogranin V |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| TMPRSS3 | transmembrane protease, serine 3 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSPAN13 | tetraspanin 13 |
| TXNIP | thioredoxin interacting protein |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACKR3 | atypical chemokine receptor 3 |
| ADRB2 | adrenoceptor beta 2, surface |
| CCND1 | cyclin D1 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CES1 | carboxylesterase 1 |
| CHGB | chromogranin B |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DUSP14 | dual specificity phosphatase 14 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FOSL1 | FOS-like antigen 1 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HOXA10 | homeobox A10 |
| HSPA2 | heat shock 70kDa protein 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| KIF1BP | KIF1 binding protein |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MATN2 | matrilin 2 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| NRG1 | neuregulin 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB2A | RAB2A, member RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SRSF6 | serine/arginine-rich splicing factor 6 |
| THBS1 | thrombospondin 1 |
| TNC | tenascin C |
| TUBB2A | tubulin, beta 2A class IIa |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 |
