| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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115 genes differentially expressed following the BRD-K20285085_fostamatinib_HS578T_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADIRF | adipogenesis regulatory factor |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| APOD | apolipoprotein D |
| ASPN | asporin |
| ATP9A | ATPase, class II, type 9A |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked |
| CEP57 | centrosomal protein 57kDa |
| COL11A1 | collagen, type XI, alpha 1 |
| COMP | cartilage oligomeric matrix protein |
| CTSK | cathepsin K |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| FOXO4 | forkhead box O4 |
| FRZB | frizzled-related protein |
| G0S2 | G0/G1 switch 2 |
| HIST1H2BD | histone cluster 1, H2bd |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) |
| IGHD | immunoglobulin heavy constant delta |
| IGHM | immunoglobulin heavy constant mu |
| IGKV1-5 | immunoglobulin kappa variable 1-5 |
| ITM2C | integral membrane protein 2C |
| KIAA1033 | KIAA1033 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAGEA3 | melanoma antigen family A3 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MTSS1 | metastasis suppressor 1 |
| MX2 | MX dynamin-like GTPase 2 |
| MYO6 | myosin VI |
| NBPF10 | neuroblastoma breakpoint family, member 10 |
| NDN | necdin, melanoma antigen (MAGE) family member |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| QPRT | quinolinate phosphoribosyltransferase |
| RAB13 | RAB13, member RAS oncogene family |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RDX | radixin |
| S100A8 | S100 calcium binding protein A8 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SOCS2 | suppressor of cytokine signaling 2 |
| SRPK2 | SRSF protein kinase 2 |
| SSR4 | signal sequence receptor, delta |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TPR | translocated promoter region, nuclear basket protein |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| Symbol | Name |
|---|---|
| AK4 | adenylate kinase 4 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATF5 | activating transcription factor 5 |
| BID | BH3 interacting domain death agonist |
| CALML5 | calmodulin-like 5 |
| CDC42 | cell division cycle 42 |
| CDC45 | cell division cycle 45 |
| CDC6 | cell division cycle 6 |
| CDK2 | cyclin-dependent kinase 2 |
| CENPU | centromere protein U |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| ECT2 | epithelial cell transforming 2 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ETNK1 | ethanolamine kinase 1 |
| EXO1 | exonuclease 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GDF15 | growth differentiation factor 15 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GOLM1 | golgi membrane protein 1 |
| GTPBP8 | GTP-binding protein 8 (putative) |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| JUN | jun proto-oncogene |
| KLF4 | Kruppel-like factor 4 (gut) |
| KRT7 | keratin 7, type II |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MCM10 | minichromosome maintenance complex component 10 |
| PCNA | proliferating cell nuclear antigen |
| PDLIM5 | PDZ and LIM domain 5 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PFKP | phosphofructokinase, platelet |
| PGC | progastricsin (pepsinogen C) |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PRC1 | protein regulator of cytokinesis 1 |
| PSCA | prostate stem cell antigen |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| S100P | S100 calcium binding protein P |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SOAT1 | sterol O-acyltransferase 1 |
| SORD | sorbitol dehydrogenase |
| SPP1 | secreted phosphoprotein 1 |
| SRPX | sushi-repeat containing protein, X-linked |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STK17A | serine/threonine kinase 17a |
| STK39 | serine threonine kinase 39 |
| TFRC | transferrin receptor |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TUBB2A | tubulin, beta 2A class IIa |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| ZDHHC6 | zinc finger, DHHC-type containing 6 |
