| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
68 genes differentially expressed following the BRD-K20492338_2-(2-amino-1H-benzo[d]imidazol-1-yl)-N-benzylquinazolin-4-amine KUC108873N_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| BMP2 | bone morphogenetic protein 2 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DENND5A | DENN/MADD domain containing 5A |
| DUSP5 | dual specificity phosphatase 5 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EZR | ezrin |
| FADS1 | fatty acid desaturase 1 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FOSL1 | FOS-like antigen 1 |
| FOSL2 | FOS-like antigen 2 |
| GATA2 | GATA binding protein 2 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HOPX | HOP homeobox |
| ICAM1 | intercellular adhesion molecule 1 |
| IER3 | immediate early response 3 |
| KDM5D | lysine (K)-specific demethylase 5D |
| LDLR | low density lipoprotein receptor |
| MAP7 | microtubule-associated protein 7 |
| MED13L | mediator complex subunit 13-like |
| MSMO1 | methylsterol monooxygenase 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SMAD3 | SMAD family member 3 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SQLE | squalene epoxidase |
| SQSTM1 | sequestosome 1 |
| TRIB3 | tribbles pseudokinase 3 |
| WDR13 | WD repeat domain 13 |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ANXA1 | annexin A1 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| CDC20 | cell division cycle 20 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CENPF | centromere protein F, 350/400kDa |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DPYD | dihydropyrimidine dehydrogenase |
| DUSP22 | dual specificity phosphatase 22 |
| GAS1 | growth arrest-specific 1 |
| HOXC6 | homeobox C6 |
| HSPA8 | heat shock 70kDa protein 8 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL17RB | interleukin 17 receptor B |
| KIF20A | kinesin family member 20A |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| PEG3 | paternally expressed 3 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PLK1 | polo-like kinase 1 |
| PTTG1 | pituitary tumor-transforming 1 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| RPL38 | ribosomal protein L38 |
| RPS11 | ribosomal protein S11 |
| SLPI | secretory leukocyte peptidase inhibitor |
| STOM | stomatin |
| TNC | tenascin C |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta |
