BRD-K20696416_NVP-AEW541_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K20696416_NVP-AEW541_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BLNK B-cell linker
CCNG2 cyclin G2
CD9 CD9 molecule
CLCA1 chloride channel accessory 1
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTGF connective tissue growth factor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
ERBB3 erb-b2 receptor tyrosine kinase 3
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOXO4 forkhead box O4
GLUL glutamate-ammonia ligase
IRS2 insulin receptor substrate 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LXN latexin
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUPR1 nuclear protein, transcriptional regulator, 1
PDGFD platelet derived growth factor D
PDK4 pyruvate dehydrogenase kinase, isozyme 4
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SMAD3 SMAD family member 3
STXBP1 syntaxin binding protein 1
TSPAN31 tetraspanin 31
TXNIP thioredoxin interacting protein
VNN1 vanin 1
WT1 Wilms tumor 1

decreased expression

Symbol Name
BID BH3 interacting domain death agonist
C20ORF24 chromosome 20 open reading frame 24
CCNE2 cyclin E2
CSE1L CSE1 chromosome segregation 1-like (yeast)
EPHA3 EPH receptor A3
LPL lipoprotein lipase
PCDH17 protocadherin 17
PGC progastricsin (pepsinogen C)
PGM1 phosphoglucomutase 1
PPIF peptidylprolyl isomerase F
SNAP25 synaptosomal-associated protein, 25kDa
TUBA4A tubulin, alpha 4a
Funding