BRD-K20742498_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

26 genes differentially expressed following the BRD-K20742498_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA10 annexin A10
BHLHE41 basic helix-loop-helix family, member e41
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CST3 cystatin C
CX3CR1 chemokine (C-X3-C motif) receptor 1
DDIT3 DNA-damage-inducible transcript 3
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM129A family with sequence similarity 129, member A
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GDF15 growth differentiation factor 15
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
INSIG1 insulin induced gene 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
MSMO1 methylsterol monooxygenase 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
SQSTM1 sequestosome 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
IGFBP3 insulin-like growth factor binding protein 3
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TSPAN13 tetraspanin 13
ZMAT3 zinc finger, matrin-type 3