| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
186 genes differentially expressed following the BRD-K20755323_-666_HA1E_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AARS | alanyl-tRNA synthetase |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACADVL | acyl-CoA dehydrogenase, very long chain |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALAS1 | 5'-aminolevulinate synthase 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANPEP | alanyl (membrane) aminopeptidase |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF4 | activating transcription factor 4 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) |
| BCL2L2 | BCL2-like 2 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CA2 | carbonic anhydrase II |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CBS | cystathionine-beta-synthase |
| CCPG1 | cell cycle progression 1 |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CHGB | chromogranin B |
| CTSL | cathepsin L |
| CYTIP | cytohesin 1 interacting protein |
| DENND1B | DENN/MADD domain containing 1B |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| ETV1 | ets variant 1 |
| ETV5 | ets variant 5 |
| FAM129A | family with sequence similarity 129, member A |
| FCGBP | Fc fragment of IgG binding protein |
| FTH1 | ferritin, heavy polypeptide 1 |
| GDF15 | growth differentiation factor 15 |
| GLRX | glutaredoxin (thioltransferase) |
| GPC1 | glypican 1 |
| GRB7 | growth factor receptor-bound protein 7 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) |
| IFNGR1 | interferon gamma receptor 1 |
| IL10RA | interleukin 10 receptor, alpha |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LST1 | leukocyte specific transcript 1 |
| LY96 | lymphocyte antigen 96 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| NDRG2 | NDRG family member 2 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PFKM | phosphofructokinase, muscle |
| PHGDH | phosphoglycerate dehydrogenase |
| PLIN2 | perilipin 2 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PRNP | prion protein |
| PRUNE2 | prune homolog 2 (Drosophila) |
| QPCT | glutaminyl-peptide cyclotransferase |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
| SIRPA | signal-regulatory protein alpha |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SPP1 | secreted phosphoprotein 1 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| SYT1 | synaptotagmin I |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TMEM176B | transmembrane protein 176B |
| TPP1 | tripeptidyl peptidase I |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM2 | tripartite motif containing 2 |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| TXNRD1 | thioredoxin reductase 1 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VEGFA | vascular endothelial growth factor A |
| WARS | tryptophanyl-tRNA synthetase |
| Symbol | Name |
|---|---|
| ACAT2 | acetyl-CoA acetyltransferase 2 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AMD1 | adenosylmethionine decarboxylase 1 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| ANXA3 | annexin A3 |
| AURKA | aurora kinase A |
| AUTS2 | autism susceptibility candidate 2 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CAV2 | caveolin 2 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD24 | CD24 molecule |
| CD47 | CD47 molecule |
| CDA | cytidine deaminase |
| CDC42 | cell division cycle 42 |
| CDCA3 | cell division cycle associated 3 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CENPA | centromere protein A |
| CLIC3 | chloride intracellular channel 3 |
| CNN3 | calponin 3, acidic |
| COL5A1 | collagen, type V, alpha 1 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
| CYTH1 | cytohesin 1 |
| DHCR24 | 24-dehydrocholesterol reductase |
| DHCR7 | 7-dehydrocholesterol reductase |
| DLC1 | DLC1 Rho GTPase activating protein |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EHD1 | EH-domain containing 1 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| ENO1 | enolase 1, (alpha) |
| EPHB2 | EPH receptor B2 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| F2R | coagulation factor II (thrombin) receptor |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H2BK | histone cluster 1, H2bk |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| INHBB | inhibin, beta B |
| INSIG1 | insulin induced gene 1 |
| KIF20A | kinesin family member 20A |
| KLF6 | Kruppel-like factor 6 |
| LAGE3 | L antigen family, member 3 |
| LAMC2 | laminin, gamma 2 |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LDLR | low density lipoprotein receptor |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LUM | lumican |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MARCKSL1 | MARCKS-like 1 |
| MATN2 | matrilin 2 |
| MLF1 | myeloid leukemia factor 1 |
| MMP7 | matrix metallopeptidase 7 |
| MSMO1 | methylsterol monooxygenase 1 |
| MYLK | myosin light chain kinase |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NPR3 | natriuretic peptide receptor 3 |
| NREP | neuronal regeneration related protein |
| PDLIM1 | PDZ and LIM domain 1 |
| PEG10 | paternally expressed 10 |
| PGC | progastricsin (pepsinogen C) |
| PLK1 | polo-like kinase 1 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| PRSS23 | protease, serine, 23 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 |
| PTTG1 | pituitary tumor-transforming 1 |
| RPL22 | ribosomal protein L22 |
| RPL37A | ribosomal protein L37a |
| S100A2 | S100 calcium binding protein A2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCEL | sciellin |
| SFN | stratifin |
| SFPQ | splicing factor proline/glutamine-rich |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SNRPE | small nuclear ribonucleoprotein polypeptide E |
| SORD | sorbitol dehydrogenase |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPRR1A | small proline-rich protein 1A |
| SQLE | squalene epoxidase |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| STMN1 | stathmin 1 |
| TAGLN2 | transgelin 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNS3 | tensin 3 |
| TUBB | tubulin, beta class I |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
