BRD-K20755323_-666_HCC515_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K20755323_-666_HCC515_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
AGR2 anterior gradient 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
C3ORF14 chromosome 3 open reading frame 14
CCNG2 cyclin G2
CD52 CD52 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHIC2 cysteine-rich hydrophobic domain 2
CNPY3 canopy FGF signaling regulator 3
COCH cochlin
CTH cystathionine gamma-lyase
CYB561 cytochrome b561
DDIT3 DNA-damage-inducible transcript 3
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSP desmoplakin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF5A eukaryotic translation initiation factor 5A
FAM129A family with sequence similarity 129, member A
FAM13A family with sequence similarity 13, member A
GATA3 GATA binding protein 3
HES1 hes family bHLH transcription factor 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HMOX1 heme oxygenase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HYOU1 hypoxia up-regulated 1
KDM5D lysine (K)-specific demethylase 5D
LSR lipolysis stimulated lipoprotein receptor
MID1IP1 MID1 interacting protein 1
NKX3-1 NK3 homeobox 1
NUPR1 nuclear protein, transcriptional regulator, 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRDX2 peroxiredoxin 2
RPS11 ribosomal protein S11
SEC24D SEC24 family member D
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TPD52L1 tumor protein D52-like 1
UGDH UDP-glucose 6-dehydrogenase
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
CAV1 caveolin 1, caveolae protein, 22kDa
CCND1 cyclin D1
CDCA4 cell division cycle associated 4
COL15A1 collagen, type XV, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
CRABP2 cellular retinoic acid binding protein 2
CTSG cathepsin G
DRAM1 DNA-damage regulated autophagy modulator 1
FABP4 fatty acid binding protein 4, adipocyte
FJX1 four jointed box 1 (Drosophila)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HOXA5 homeobox A5
HOXB6 homeobox B6
KIF20A kinesin family member 20A
LAMP1 lysosomal-associated membrane protein 1
LOXL2 lysyl oxidase-like 2
MYOF myoferlin
PALMD palmdelphin
PEG10 paternally expressed 10
PLK1 polo-like kinase 1
PON2 paraoxonase 2
RGS2 regulator of G-protein signaling 2
SFRP1 secreted frizzled-related protein 1
SPARCL1 SPARC-like 1 (hevin)
SRSF7 serine/arginine-rich splicing factor 7
STMN1 stathmin 1
XIST X inactive specific transcript (non-protein coding)
Funding