| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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146 genes differentially expressed following the BRD-K20755323_-666_MDST8_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ALCAM | activated leukocyte cell adhesion molecule |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ASRGL1 | asparaginase like 1 |
| ATF4 | activating transcription factor 4 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| CA2 | carbonic anhydrase II |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CDC42 | cell division cycle 42 |
| CHEK2 | checkpoint kinase 2 |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CTSZ | cathepsin Z |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EIF5A | eukaryotic translation initiation factor 5A |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| GSE1 | Gse1 coiled-coil protein |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2BG | histone cluster 1, H2bg |
| HMOX1 | heme oxygenase 1 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM2 | interferon induced transmembrane protein 2 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| JADE3 | jade family PHD finger 3 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KLHL24 | kelch-like family member 24 |
| KRT18 | keratin 18, type I |
| LXN | latexin |
| MAGEB2 | melanoma antigen family B2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MSX1 | msh homeobox 1 |
| MUC16 | mucin 16, cell surface associated |
| NPEPL1 | aminopeptidase-like 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PIP | prolactin-induced protein |
| PLAT | plasminogen activator, tissue |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRAME | preferentially expressed antigen in melanoma |
| PSENEN | presenilin enhancer gamma secretase subunit |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| SCARB2 | scavenger receptor class B, member 2 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SRSF6 | serine/arginine-rich splicing factor 6 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STC2 | stanniocalcin 2 |
| STK10 | serine/threonine kinase 10 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TPD52 | tumor protein D52 |
| TRAM1 | translocation associated membrane protein 1 |
| UBE2M | ubiquitin-conjugating enzyme E2M |
| UGDH | UDP-glucose 6-dehydrogenase |
| USP3 | ubiquitin specific peptidase 3 |
| VCAN | versican |
| XBP1 | X-box binding protein 1 |
| ZNF331 | zinc finger protein 331 |
| Symbol | Name |
|---|---|
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANOS1 | anosmin 1 |
| ASS1 | argininosuccinate synthase 1 |
| BMP2 | bone morphogenetic protein 2 |
| C3ORF14 | chromosome 3 open reading frame 14 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD2 | CD2 molecule |
| CD24 | CD24 molecule |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CENPU | centromere protein U |
| CLTB | clathrin, light chain B |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXADR | coxsackie virus and adenovirus receptor |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DEFA4 | defensin, alpha 4, corticostatin |
| DHCR24 | 24-dehydrocholesterol reductase |
| DSG1 | desmoglein 1 |
| DST | dystonin |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FABP7 | fatty acid binding protein 7, brain |
| FAM129A | family with sequence similarity 129, member A |
| FBLN1 | fibulin 1 |
| FERMT1 | fermitin family member 1 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOPX | HOP homeobox |
| HSPA1A | heat shock 70kDa protein 1A |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| INSIG1 | insulin induced gene 1 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KRT15 | keratin 15, type I |
| KRT5 | keratin 5, type II |
| KRT6B | keratin 6B, type II |
| LDLR | low density lipoprotein receptor |
| LMNA | lamin A/C |
| LRRN3 | leucine rich repeat neuronal 3 |
| LYZ | lysozyme |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 |
| MGP | matrix Gla protein |
| MSMO1 | methylsterol monooxygenase 1 |
| MXRA5 | matrix-remodelling associated 5 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PEG10 | paternally expressed 10 |
| PKP1 | plakophilin 1 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 |
| RBPMS | RNA binding protein with multiple splicing |
| RGS5 | regulator of G-protein signaling 5 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SNAI2 | snail family zinc finger 2 |
| SNX7 | sorting nexin 7 |
| SQLE | squalene epoxidase |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TFF1 | trefoil factor 1 |
| TFF3 | trefoil factor 3 (intestinal) |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TNC | tenascin C |
| TPSAB1 | tryptase alpha/beta 1 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TYRP1 | tyrosinase-related protein 1 |
| VSNL1 | visinin-like 1 |
