| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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111 genes differentially expressed following the BRD-K21025364_NVP-TAE226_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANKRD28 | ankyrin repeat domain 28 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| CBS | cystathionine-beta-synthase |
| CCNG1 | cyclin G1 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CERS6 | ceramide synthase 6 |
| CPD | carboxypeptidase D |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FABP1 | fatty acid binding protein 1, liver |
| FAM63A | family with sequence similarity 63, member A |
| FOXN3 | forkhead box N3 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GOLGA8A | golgin A8 family, member A |
| GOLGA8B | golgin A8 family, member B |
| GOLM1 | golgi membrane protein 1 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| KIAA0485 | uncharacterized LOC57235 |
| LOX | lysyl oxidase |
| MAP1B | microtubule-associated protein 1B |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase |
| MME | membrane metallo-endopeptidase |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| MTSS1 | metastasis suppressor 1 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) |
| NNMT | nicotinamide N-methyltransferase |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDZK1 | PDZ domain containing 1 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PHGDH | phosphoglycerate dehydrogenase |
| PLSCR4 | phospholipid scramblase 4 |
| PRAME | preferentially expressed antigen in melanoma |
| PTX3 | pentraxin 3, long |
| RBKS | ribokinase |
| RGS10 | regulator of G-protein signaling 10 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| STC2 | stanniocalcin 2 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| TF | transferrin |
| TMEM140 | transmembrane protein 140 |
| TSPAN6 | tetraspanin 6 |
| TWF2 | twinfilin actin binding protein 2 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ANXA3 | annexin A3 |
| CADM1 | cell adhesion molecule 1 |
| CCNA2 | cyclin A2 |
| CD24 | CD24 molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CDC20 | cell division cycle 20 |
| CDK1 | cyclin-dependent kinase 1 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CLU | clusterin |
| COL4A6 | collagen, type IV, alpha 6 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| DUSP5 | dual specificity phosphatase 5 |
| EFNB2 | ephrin-B2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FEN1 | flap structure-specific endonuclease 1 |
| FOSL1 | FOS-like antigen 1 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| H2AFX | H2A histone family, member X |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IER3 | immediate early response 3 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KLK5 | kallikrein-related peptidase 5 |
| LMO4 | LIM domain only 4 |
| LOXL1 | lysyl oxidase-like 1 |
| LUM | lumican |
| MCAM | melanoma cell adhesion molecule |
| MELK | maternal embryonic leucine zipper kinase |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| ODC1 | ornithine decarboxylase 1 |
| PNP | purine nucleoside phosphorylase |
| S100A2 | S100 calcium binding protein A2 |
| S100A6 | S100 calcium binding protein A6 |
| SIK1 | salt-inducible kinase 1 |
| SMC4 | structural maintenance of chromosomes 4 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| STMN1 | stathmin 1 |
| TAGLN2 | transgelin 2 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 |
| TPSAB1 | tryptase alpha/beta 1 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TSPAN13 | tetraspanin 13 |
| TUBA4A | tubulin, alpha 4a |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB3 | tubulin, beta 3 class III |
| TUBB4B | tubulin, beta 4B class IVb |
| TYMS | thymidylate synthetase |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| ZWINT | ZW10 interacting kinetochore protein |
